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Bis(tributyltin)+oxide
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Bis(tributyltin)+oxide
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Bis(trifluoromethanesulfonyl)imide 99%
Supplier:
AMBEED, INC
Description:
2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Naphthol AS-BI phosphate 93%
Supplier:
APOLLO SCIENTIFIC
Description:
2,5-Bis(trifluoromethyl)benzyl bromide
Catalog Number:
(10749-856)
Supplier:
Prosci
Description:
TIGAR Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. Recent studies have demonstrated the ability of p53 to regulate the expression of several proteins involved in glycolysis and oxidative phosphorylation, such as TIGAR, SCO2, and phosphoglycerate mutase. TIGAR is a recently discovered protein that functions to regulate glycolysis and protect cells against oxidative stress. TIGAR is similar in structure to proteins in the phosphoglycerate mutase family, most notably 6-phosphofructo-2-kinase, suggesting TIGAR may function as a fructose bisphosphatase. Expression of TIGAR in transfected cells correlated with an inhibition of glycolysis and decreased levels of reactive oxygen species and p53-induced apoptosis, indicating that TIGAR may act to modulate the apoptotic response to p53, thereby allowing cells to survive mild or transient stresses.
Catalog Number:
(10464-124)
Supplier:
Bioss
Description:
Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
Supplier:
AMBEED, INC
Description:
Bis(4-nitrophenyl)amine 96%
Catalog Number:
(10750-616)
Supplier:
Prosci
Description:
FAM120A Antibody: FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.
Catalog Number:
(10671-748)
Supplier:
Bioss
Description:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Bis(phenylsulfonyl)sulfide 96%
Supplier:
AGILENT TECHNOLOGIES, INC (CSD)
Description:
Agilent J&W HP-PLOT AL₂O₃ M is the most polar aluminum oxide phase deactivated with proprietary deactivation.
Supplier:
TCI America
Description:
Bis[(pinacolato)boryl]methane, Purity: >95.0%(GC), Cas number: 78782-17-9, Molecular Formula: C13H26B2O4, Molecular Weight: 267.97, Appearance: White - Almost white solid crystal lump, Synonyms: Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane, Size: 1G
Catalog Number:
(80058-034)
Supplier:
MilliporeSigma
Description:
A reversible inhibitor of nitric oxide synthase in vitro (IC50 = 2-3uM) and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects. Purity: >98% by TLC. Soluble in water. CAS: 65005-57-4. FW: 275.2. 25mg white solid.
Supplier:
Thermo Scientific Chemicals
Description:
2,4-Bis(trifluoromethyl)phenylboronic acid. Grade: 97. Melting Point C. Boiling Point C: NA. C8H5BF6O2. 153254-09-2. IRRITANT
Catalog Number:
(76109-900)
Supplier:
Bioss
Description:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
Supplier:
Thermo Scientific Chemicals
Description:
For bleaching and deodorizing textiles, wood, hair, etc; rocket propulsion; maturing agent in food; water and sewage treatment; disinfectant; laboratory reagent
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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