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Bis(tributyltin)+oxide
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Bis(tributyltin)+oxide
Supplier:
Strem Chemicals Inc
Description:
Metallocenes, Derivatives & Cp Precursors, Volatile Organometallics for CVD & ALD, Volatile Precursors for CVD
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 75203-51-9, MDL: MFCD00012038
Catalog Number:
(10235-716)
Supplier:
Bioss
Description:
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. May participate in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.
Supplier:
Strem Chemicals Inc
Description:
Metallocenes, Derivatives & Cp Precursors
Supplier:
Strem Chemicals Inc
Description:
JOSIPHOS, Phosphine
Supplier:
AMBEED, INC
Description:
N,N'-((9H-Fluorene-9,9-diyl)bis(4,1-phenylene))bis(N-([1,1'-biphenyl]-4-yl)-[1,1'-biphenyl]-4-amine), Purity: 97%, CAS Number: 174141-92-5, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 250mg
Supplier:
TCI America
Description:
CAS Number: 6941-69-1
MDL Number: MFCD00045277 Molecular Formula: C6H8Cl2O4 Molecular Weight: 215.03 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 158 Melting point (°C): 41
Supplier:
Strem Chemicals Inc
Description:
Phosphine, Pincer Ligands and Complexes
Catalog Number:
(77602-318)
Supplier:
AMBEED, INC
Description:
Triphenyl phosphate 99%
Catalog Number:
(AAH26897-03)
Catalog Number:
(102514-620)
Supplier:
Adipogen
Description:
NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
Catalog Number:
(10408-090)
Supplier:
Bioss
Description:
ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
Catalog Number:
(101913-808)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 057963-5G , MDL Number: MFCD01321334
Supplier:
MP Biomedicals
Description:
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue.
It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production. Store at Room Temperature(15-30 °C), desiccate
Supplier:
AMBEED, INC
Description:
5',5''-Bis(4-carboxyphenyl)-[1,1':3',1'':3'',1'''-quaterphenyl]-4,4'''-dicarboxylic acid, Purity: 98%, CAS Number: 1383925-31-2, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 5g
Supplier:
Strem Chemicals Inc
Description:
Jacobsen Ligand
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