2-(Aminomethyl)-3,5-difluoropyridine+dihydrochloride
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Catalog Number:
(IC15349250)
Supplier:
MP Biomedicals
Description:
Dilute in 10 mM Tris-HCl buffer, pH 8.0 containing 2 mM EDTA and 1.0% KCl.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
L-Phenylalanine ethyl ester hydrochloride 99%
Catalog Number:
(TCT2693-25G)
Supplier:
TCI America
Description:
CAS Number: 116-02-9
MDL Number: MFCD00019378
Molecular Formula: C9H18O
Molecular Weight: 142.24
Purity/Analysis Method: <gt/>80.0% (GC)
Form: Crystal
Color: White
Boiling point (°C): 86
Melting point (°C): 34
Flash Point (°C): 88
Supplier:
AMBEED, INC
Description:
D-Homophenylalanine ethyl ester hydrochloride 97%
Supplier:
TCI America
Description:
CAS Number: 2644-70-4
MDL Number: MFCD00044368 Molecular Formula: H4N2 Molecular Weight: 68.50 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 93
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Methyl-L-threoninate hydrochloride 98+%
Supplier:
Adipogen
Description:
A-674563 is a potent, orally available Akt1 inhibitor with an IC(50) of 11nM. It also displays activity against PKA and CDK2 with IC(50) values of 16 and 46nM respectively.
Supplier:
BeanTown Chemical
Description:
CAS: 14592-56-4; EC No: 238-637-3; MDL No: MFCD00013122
UN No: UN3439; Haz Class: 6.1; Packing Group: III
Powder; Linear Formula: PdCl2(CH3CN)2; Molecular Formula: C4H6Cl2N2Pd; MW: 259.43
Catalog Number:
(103265-390)
Supplier:
Southern Biotechnology
Description:
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
Catalog Number:
(103265-388)
Supplier:
Southern Biotechnology
Description:
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
Catalog Number:
(77697-019)
Supplier:
LGC STANDARDS
Description:
N-Ethylbuphedrone Hydrochloride (NEB HCl; alpha-Ethylaminobutyrophenone Hydrochloride) 1.0 mg/ml in Methanol (as free base), LoGiCal, LGC Standards
Catalog Number:
(103458-884)
Supplier:
HCL Label
Description:
HCL's Warning may form explosive peroxide label will enhance safe handling of peroxides and is a durable, well-made label.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
DL-Alanine methyl ester hydrochloride 98+%
Supplier:
Biolegend
Description:
APC anti-human CD22 [S-HCL-1]; Isotype: Mouse IgG2b, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Supplier:
BeanTown Chemical
Description:
CAS: 15430-52-1; EC No: 239-440-5; MDL No: MFCD00012907
UN No: UN2811; Haz Class: 6.1; Packing Group: II
Powder; Linear Formula: HC≡CCH2NH2·HCl; Molecular Formula: C3H5N·HCl; MW: 91.54
Melting Point: 179-182°
Hygroscopic
Catalog Number:
(10303-850)
Supplier:
Bioss
Description:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
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