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Catalog Number:
(102511-378)
Supplier:
Adipogen
Description:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Catalog Number:
(75843-904)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The WM-15 monoclonal antibody specifically reacts with human CD13, 150-170 type II transmembrane ectoenzyme also named aminopeptidase N and gp150. It is expressed by granulocytes and monocytes, epithelial cells, and endothelial cells. CD13 plays a role in the terminal degradation of peptides, antigen processing, and chemokine cleavage, and cellular adhesion.
Catalog Number:
(76119-192)
Supplier:
Bioss
Description:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
Supplier:
BeanTown Chemical
Description:
CAS: 625-45-6; EC No: 210-894-6; MDL No: MFCD00004308; RTECS: AI8650000
UN No: UN3265; Haz Class: 8; Packing Group: II
Liquid; Linear Formula: CH3OCH2COOH; MW: 90.08
Melting Point: 7-9°; Boiling Point: 202-204°; Flash point: 121°C (250°F)
Density (g/mL): 1.174; Refractive Index: 1.417
Catalog Number:
(10105-814)
Supplier:
Prosci
Description:
SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.
Catalog Number:
(10103-644)
Supplier:
Prosci
Description:
UGT2A3 is a single-pass type I membrane proteinPotential. It belongs to the UDP-glycosyltransferase family. UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Supplier:
BeanTown Chemical
Description:
CAS: 816-40-0; EC No: 212-431-3; MDL No: MFCD00000207; RTECS: EL7000000
UN No: UN2927; Haz Class: 6.1 (8); Packing Group: II
Liquid; Molecular Formula: C4H7BrO; MW: 151.00
Boiling Point: 105°/150 mmHg; Flash point: 68°C (154°F)
Density (g/mL): 1.479; Refractive Index: 1.465
Supplier:
BeanTown Chemical
Description:
CAS: 7188-38-7; EC No: 230-553-5; MDL No: MFCD00000002; RTECS: EQ7102500
UN No: UN1992; Haz Class: 3 (6.1); Packing Group: II
Liquid; Linear Formula: (CH3)3CNC; MW: 83.13
Boiling Point: 90-92°; Flash point: -2°C (28°F)
Density (g/mL): 0.735; Refractive Index: 1.376
Catalog Number:
(75793-988)
Supplier:
Prosci
Description:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Supplier:
BeanTown Chemical
Description:
CAS: 77-76-9; EC No: 201-056-0; MDL No: MFCD00008479
UN No: UN3271; Haz Class: 3; Packing Group: II
Liquid; Linear Formula: (CH3O)2C(CH3)2; Molecular Formula: C5H12O2; MW: 104.15
Boiling Point: 83°; Flash point: -10°C (14°F)
Density (g/mL): 0.847; Refractive Index: 1.378
Supplier:
BeanTown Chemical
Description:
CAS: 78-93-3; EC No: 201-159-0; MDL No: MFCD00011648; RTECS: EL6475000
UN No: UN1193; Haz Class: 3; Packing Group: II
Liquid; Molecular Formula: C4H8O; MW: 72.11
Melting Point: -87°; Boiling Point: 80°; Flash point: -3°C (27°F)
Density (g/mL): 0.805; Refractive Index: 1.379
Catalog Number:
(76109-006)
Supplier:
Bioss
Description:
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Supplier:
Bachem Americas
Description:
PAR peptides (TRAP peptides and thrombin receptor-like peptides) activate the proteinase-activated receptors PAR-1 to PAR-4.
Catalog Number:
(10782-096)
Supplier:
Biosensis
Description:
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. The Spectrins form into dimers and further into tetramers of alpha and beta subunits (Ref: Entrez Gene). The alpha-II subunit is widely expressed in tissues but, in the nervous system, is found predominantly in neurons.
Catalog Number:
(76108-566)
Supplier:
Bioss
Description:
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Supplier:
BeanTown Chemical
Description:
CAS: 75-05-8; EC No: 200-835-2; MDL No: MFCD00001878; RTECS: AL7700000
UN No: UN1648; Haz Class: 3; Packing Group: II
Liquid; Linear Formula: CH3CN; MW: 41.05
Melting Point: -48°; Boiling Point: 81-82°; Flash point: 2°C (36°F)
Density (g/mL): 0.786; Refractive Index: 1.344
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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