2-Azatricyclo[3.3.1.13,7]decane-5-carboxylic acid methyl ester hy
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Dichloropyridine 98%
Supplier:
AMBEED, INC
Description:
2,4-Difluorobenzylamine 98%
Catalog Number:
(101971-332)
Supplier:
MORAVEK BIOCHEMICALS MS
Description:
Pentane-2,4-dione, [2,4-14C] ≥98% (by HPLC), MORpure™
Catalog Number:
(80055-978)
Supplier:
MilliporeSigma
Description:
A natural dietary compound reported to have anticarcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50=3.7µM). Inhibits Ca2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
Catalog Number:
(77624-364)
Supplier:
AMBEED, INC
Description:
2,4-Dibromoanisole ≥99%
Supplier:
AOB CHEM USA
Description:
2,4-Dimethoxytoluene ≥97%
Catalog Number:
(102991-276)
Supplier:
Adipogen
Description:
CD14/TLR4 antagonist. Inhibitor of sterile inflammation. Synthetic TLR4/CD14 ligand with TLR4 modulating activities in vitro, and conferring protection against TLR4/CD14-mediated tissue damage and inflammation in vivo. Useful to explore CD14- dependent and TLR4-independent pathways and TLR4 activation by endogenous ligands (e.g. hyaluronic acid oligosaccharides, oxLDL, HMGB1) in sterile inflammation. Shown to inhibit neuropathic pain, secondary necrosis of acute drug-induced liver failure and vascular inflammation, and abdominal aortic aneurysm by blocking non-hematopoietic TLR4 signaling. Useful tool, where inhibition of sterile (auto-) inflammation is desired, without compromising TLR4’s key role in the defense of pathogens.
Supplier:
Adipogen
Description:
(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. In binding assays, (+)-JQ1 binds competitive with acetyl lysine to BRD4 bromodomain 1 (Kd=50nM) and and BRD4 bromodomain 2 (Kd=90 nM). May be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. (+)-JQ1 exhibited strong dose- and time-dependent inhibition of BRDT, a bromodomain-containing protein highly enriched in testis. BRDT is involved in chromatin remodeling and is essential for healthy sperm development. (+)-JQ1 appears to block that function and causes a decrease in sperm viability, being examined as a potential male contraceptive. Inhibitor of inflammation and bone destruction.
Supplier:
Spectrum Chemicals
Description:
2,4-Dinitrophenylhydrazine is a chemical compound that is usually supplied as a wet red-to-orange solid that is shock sensitive. It is used in Brady's test to detect the carbonyl functionality of an aldehyde or ketone functional group
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
α,2,4-Trichlorotoluene 99%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Xylenol 99%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Difluorobenzylamine 98%
Supplier:
AMBEED, INC
Description:
2,4-Dimethoxyquinoline 95%
Catalog Number:
(MFLX34002-24)
Supplier:
VWR International
Description:
Connect even the smallest tubing with a leak-free seal from vacuum to pressure.
Supplier:
AMBEED, INC
Description:
2,4-Dichloroquinoline 98%
Catalog Number:
(102841-370)
Supplier:
Matrix Scientific
Description:
2,4-Dichloro-6-nitroquinoline 97
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