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H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(77746-643)
Supplier:
AMBEED, INC
Description:
Reserpine hydrochloride ≥98%
Catalog Number:
(10391-398)
Supplier:
Bioss
Description:
Chk2 is a serine/threonine kinase involved in the control of cell cycle checkpoints, and may also participate in transduction of the DNA damage and replicational stress signals. Chk2 is the mammalian ortholog of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases. The amino-terminal domain of Chk2 contains a series of seven serine and threonine residues (Ser19, Thr26, Ser28, Ser33, Ser35, Ser50 and Thr68) followed by glutamine (SQ or TQ motif). These are known to be preferred sites for phosphorylation by ATM/ATR kinases. Indeed, after DNA damage by ionizing radiation (IR), UV irradiation or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. Phosphorylation at Thr68 is a prerequisite for the subsequent activation step, which is attributable to autophosphorylation of Chk2 on residues Thr383 and Thr387 in the activation loop of the kinase domain. Chk2 inhibits CDC25C phosphatase by phosphorylating it on Ser-216, preventing the entry into mitosis. This kinase may have a role in meiosis as well. Kinase activity is up regulated by autophosphorylation and the protein is rapidly phosphorylated in response to DNA damage and to replication block.
Supplier:
Rockland Immunochemical
Description:
Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of nucleic acids.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Labetalol EP Impurity G HCl (Mixture of Diastereomers)
Supplier:
ALADDIN SCIENTIFIC
Description:
Amiloride ? HCl is a selective T-type calcium channel protein inhibitor that has been shown to inhibit the Polycystin-L channel (Polycystic kidney disease 2-like 1 protein: PKD2L1), a member of the transient receptor potential (TRP) superfamily of cation channels, including the NHE (sodium/hydgrogen exchanger). Amiloride is also an epithelial sodium channel protein inhibitor, which inhibits sodium reabsorption without affecting potassium concentrations. Amiloride serves as a non-selective acid-sensing ion channel (ASIC) blocker and a selective inhibitor of uPA (urokinase plasminogen activator). Research shows that amiloride reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 μM. Amiloride ? HCl is an inhibitor of Sodium/Potassium-ATPase Protein.A calcium channel andsodium channel protein inhibitor
Catalog Number:
(101909-100)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054930-1G , MDL Number: MFCD14525530
Supplier:
Matrix Scientific
Description:
MF=C4Hcl3F6 MW=269.40 MDL=MFCD02093295 5G
Supplier:
AMBEED, INC
Description:
Acetyl-L-carnitine hydrochloride 97%
Supplier:
AMBEED, INC
Description:
7-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride, Purity: 95%, CAS Number: 799274-06-9, Appearance: Form: solid, Storage: Inert atmosphere, Room Temperature, Size: 100mg
Supplier:
BeanTown Chemical
Description:
CAS: 7379-35-3; EC No: 230-946-1; MDL No: MFCD00012829; RTECS: US6300000
Solid; Molecular Formula: C5H4ClN·HCl ; MW: 150.01
Melting Point: 210° (sublimes); Flash point: 198°C (388°F)
Supplier:
LGC STANDARDS
Description:
Aluminum AA Standard: Al @ 1000 µg/mL in 5% HCl, VHG, LGC Standards
Supplier:
AMBEED, INC
Description:
3-Methylphenylhydrazine hydrochloride, Purity: 97%, CAS Number: 637-04-7, Appearance: Form: Crystal - Powder, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 5g
Catalog Number:
(103006-524)
Supplier:
Anaspec Inc
Description:
HiLyteâ„¢ Fluor 488 hydroxylamine is a carbonyl-reactive labeling dye, which reacts more readily with aldehydes at physiological pH than other primary amine-containing reagents (such as hydrazides and amines).
Catalog Number:
(102838-662)
Supplier:
Matrix Scientific
Description:
DL-2,4-Diaminobutyric acid dihydrochloride ≥97%
Catalog Number:
(101909-212)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 055415-1G , MDL Number: MFCD08436597
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 007200-25G , MDL Number: MFCD02184272
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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