GNE-493
Supplier:
Adipogen
Description:
GNE-493 is a potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor for the treatment of cancer.
Supplier:
AMBEED, INC
Description:
2-(2-(2-Aminopyrimidin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol, Purity: 98+%, CAS Number: 1033735-94-2, Appearance: White to yellow powder or crystals, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 1mg
Supplier:
Adipogen
Description:
GNE 477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC(50) value of 4nM and 21nM respectively.
Supplier:
AMBEED, INC
Description:
GNE-140 98%
Supplier:
AMBEED, INC
Description:
(4-((4-(Ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-fluoro-5-methoxyphenyl)(morpholino)methanone, Purity: 98+%, CAS Number: 1351761-44-8, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 5mg
Supplier:
Adipogen
Description:
GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR. It has good pharmacokinetic (PK) parameters and demonstrates knock down of pathway markers in vivo. Originally obtained via modification of compounds like GDC-0941, GNE-490 which have a significantly reduced potency mTOR while maintaining effective potency for PI3K substrates. IC(50) values for PI3K family members are in the subnanomolar to low nanomolar range (-.28 to <lt/>20nm) while IC(50) values for mTOR and other related tyrosine kinases are greater than 750nM with most being greater than 1µM or more, thus GNE-490 makes a good choice for examining PI3K related events separate from those mediated by mTOR.
Catalog Number:
(76756-328)
Supplier:
Prosci
Description:
Anti-GNE Rabbit Polyclonal Antibody
Catalog Number:
(102869-420)
Supplier:
R&D Systems
Description:
The Recombinant Human N-Acetylmannosamine Kinase/GNE Protein from R&D Systems is derived from E. coli. The Recombinant Human N-Acetylmannosamine Kinase/GNE Protein has been validated for the following applications: Enzyme Activity.
Supplier:
AMBEED, INC
Description:
5-(6-(3-Methoxyoxetan-3-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine, Purity: 98%, CAS Number: 1394076-92-6, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 10mg
Catalog Number:
(89380-932)
Supplier:
Abgent
Catalog Number:
(77054-362)
Supplier:
ANTIBODIES.COM LLC
Description:
Rabbit polyclonal antibody to GNE for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Supplier:
AMBEED, INC
Description:
2-((6-(3,3-Difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile, Purity: 98+%, CAS Number: 1496581-76-0, Appearance: Yellow solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 10mg
Catalog Number:
(10557-650)
Supplier:
Abnova
Description:
GNE polyclonal antibody (A01), Mouse polyclonal antibody raised against a partial recombinant GNE, Size: 50ul
Catalog Number:
(102242-202)
Supplier:
Novus Biologicals
Description:
GNE Lysate (Adult Normal)
Catalog Number:
(77848-725)
Supplier:
AFG BIOSCIENCE LLC
Description:
Anti-GNE Rabbit Polyclonal Antibody
Supplier:
AMBEED, INC
Description:
6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide 98%
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