H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(103680-884)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human FAM3B isoform B (P58499-1) (Met 1-Ser 235) was fused with the Fc region of human IgG1 at the C-terminus.
Catalog Number:
(103617-774)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Human GRK5 (rh GRK5; Catalog#10839-H08B; NP_005299.1; Met 1-Ser 590). GRK5 specific IgG was purified by Human GRK5 affinity chromatography.
Catalog Number:
(10472-772)
Supplier:
Bioss
Description:
PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.
Catalog Number:
(10472-782)
Supplier:
Bioss
Description:
PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.
Supplier:
AMBEED, INC
Description:
H-D-Ala-OiPr·HCl 95%
Supplier:
ACROBIOSYSTEMS INC MS
Description:
Human Nectin-4 Protein, Fc Tag, ACROBiosystems
Catalog Number:
(10420-342)
Supplier:
Bioss
Description:
Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.
Catalog Number:
(103612-944)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Supplier:
Sino Biological
Description:
A DNA sequence encoding the mature form of mouse IL1β (P10749) (Val 118-Ser 269) was expressed, with an initial Met at the C-terminus.
Catalog Number:
(103616-536)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Human HGF (rh HGF; Catalog#10463-HNAS; NP_000592.3; Met 1-Ser 728). HGF specific IgG was purified by Human HGF affinity chromatography.
Catalog Number:
(103617-836)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Human LIFR / CD118 (rh LIFR; Catalog#10628-H08H; NP_001121143.1; Met 1-Ser 833). LIFR specific IgG was purified by human LIFR affinity chromatography.
Supplier:
Bachem Americas
Description:
This fluorogenic HIV-1 protease substrate consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH₂-termini. The γ-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm.
Catalog Number:
(89162-576)
Supplier:
Enzo Life Sciences
Description:
Potent and effective inhibitor of Golgi processing mannosidase II.
Catalog Number:
(103659-382)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Mouse Ephrin-B1 / EFNB1 (rM Ephrin-B1 / EFNB1; Catalog#50580-M08H; NP_034240.1; Met 1-Ser 229). Ephrin-B1 / EFNB1 specific IgG was purified by Mouse Ephrin-B1 / EFNB1 affinity chromatography.
Catalog Number:
(102538-568)
Supplier:
Matrix Scientific
Description:
MF=C3H7NO3 MW=105.09 CAS=302-84-1 MDL=MFCD00064223 100G
Catalog Number:
(10415-494)
Supplier:
Bioss
Description:
MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family, (MAP kinase kinase family). It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, and not with another MAP kinase like P38. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). It is not phosphorylated by RAFA, RAFB or RAFC and it may interact with GTPases such as CDC42. The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle.
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