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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(76080-760)
Supplier:
Bioss
Description:
This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
Catalog Number:
(10351-036)
Supplier:
Bioss
Description:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
Catalog Number:
(76077-802)
Supplier:
Bioss
Description:
This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
Catalog Number:
(77746-737)
Supplier:
AMBEED, INC
Description:
H-4-Pal-OH·2HCl ≥98%
Catalog Number:
(AAH65370-03)
Supplier:
Thermo Scientific Chemicals
Description:
b-Homoglutamic acid hydrochloride, 97%
Catalog Number:
(TS42892-1000)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Hydrogen chloride 1 M in ethyl acetate, AcroSeal™
Supplier:
Thermo Scientific Chemicals
Description:
L-Alanine benzyl ester hydrochloride, 98%
Catalog Number:
(89161-370)
Supplier:
Enzo Life Sciences
Description:
Ultrapotent, highly selective inhibitor of cGMP-inhibited phosphodiesterase (PDE lll, IC50=0.3nM) in vitro. Potentiates adenosine-stimulated cAMP accumulation.
Supplier:
Thermo Fisher Scientific Chemicals Inc.
Description:
500 gm
Supplier:
BeanTown Chemical
Description:
CAS: 5456-63-3; MDL No: MFCD00001490
Powder; Linear Formula: H2NC6H4OH·HCl; Molecular Formula: C6H13NO·HCl; MW: 151.64
Melting Point: 172-175°
Hygroscopic
Catalog Number:
(77103-538)
Supplier:
AMBEED, INC
Description:
3,4-Dichloro-1H-pyrrole-2,5-dione 95%
Catalog Number:
(76099-618)
Supplier:
Bioss
Description:
C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Supplier:
Anaspec Inc
Description:
This cyclic peptide is a potent vasodilator. It is more powerful than the linear GRGDSP in changing the vascular tone of arterioles isolated from rat cremaster muscle.
Sequence:GRGDSP, N to C cyclized MW:569.6 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(77692-351)
Supplier:
LGC STANDARDS
Description:
4-MeO-PCP HCl (4-Methoxyphencyclidine Hydrochloride) 1.0 mg/ml in Methanol (as free base), LoGiCal, LGC Standards
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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