H-d-Ser(tBu)-OMe·HCl
Supplier:
Adipogen
Description:
LY333531 is a potent, selective inhibitor of Protein Kinase C isozymes, PKCbetaI (IC(50) of 4.7nM) and PKCbetaII (IC(50) of 5.9nM).
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054714-1G , MDL Number: MFCD04114434
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 056392-1G , MDL Number: MFCD04114449
Supplier:
AMBEED, INC
Description:
N-Methyl-D-proline Hydrochloride 95%, Ambeed.Inc
Supplier:
ALADDIN SCIENTIFIC
Description:
4-[2-(Dimethylamino)ethoxy]benzylamine is an impurity of Itopride (HCl: I931500), a gastroprokinetic benzamide derivative that is used to treat patients with dyspepsia.
Supplier:
Ricca Chemical
Description:
Certified reference material (CRM) for AA (atomic absorption)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Aniline hydrochloride 99%
Supplier:
LGC STANDARDS
Description:
Arsenic (III) Standard: As+3 @ 100 µg/mL in 2% HCl, VHG, LGC Standards
Supplier:
TCI America
Description:
CAS Number: 10052-47-8
MDL Number: MFCD00059972 Molecular Formula: C7H18ClN Molecular Weight: 151.68 Purity/Analysis Method: >98.0% (T) Form: Crystal
Catalog Number:
(10260-878)
Supplier:
Bioss
Description:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Miconazole EP Impurity C HCl (Miconazole USP Related Compound C)
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 65550-32-5, MDL: MFCD09991690
Catalog Number:
(AAH57789-03)
Catalog Number:
(10296-094)
Supplier:
Bioss
Description:
Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER). Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway. It specifically removes the distal alpha 1,2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor. Glucosidase I contains a short cytosolic tail, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER. Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), which is characterized by generalized hypotonia, dysmorphic features, hepatomegaly, hypoventilation, feeding problems, seizures and death. Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, namely Arg486Thr and Phe652Leu, that affect polypeptide folding and active site formation.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
cis-Atropine N-Oxide HCl, TLC Pharmaceutical Standards
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