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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Supplier:
AMBEED, INC
Description:
Fmoc-D-Arg-OH 95%
Catalog Number:
(10326-622)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. Binding of vascular growth factors to isoform 1 or isoform 2 leads to the activation of several signaling cascades; isoform 2 seems to be less efficient in signal transduction, because it has a truncated C-terminus and therefore lacks several phosphorylation sites. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.
Catalog Number:
(10326-632)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. Binding of vascular growth factors to isoform 1 or isoform 2 leads to the activation of several signaling cascades; isoform 2 seems to be less efficient in signal transduction, because it has a truncated C-terminus and therefore lacks several phosphorylation sites. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.
Supplier:
TCI America
Description:
Chloroformamidine Hydrochloride, CAS Number: 29671-92-9, Purity: 98.0% Pure, Molecular Formula: CH3ClN2.HCl, Molecular Weight: 114.96 g/mol, Physical Form: Solid, Size: 5G
Supplier:
AMBEED, INC
Description:
Methyl-4-amino-1-methyl-1H-pyrrole-2-carboxylate hydrochloride 98%
Catalog Number:
(97061-478)
Supplier:
VWR
Description:
A fluorescent stain for nucleic acids in agarose and polyacrylamide gels. Concentrations of 120 ?M will detect DNA at levels of 25-50 ng per band. Also used for to localize nucleic acids in a variety of cell types
Supplier:
Thermo Scientific Chemicals
Description:
Molecular Formula: Matrix: 5% HCl/tr. HF
Physical Form: Liquid UN No.: 3264 MDL No.: MFCD00151265
Catalog Number:
(10314-830)
Supplier:
Bioss
Description:
C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Catalog Number:
(TCL0216-5G)
Supplier:
TCI America
Description:
CAS Number: 98079-52-8
MDL Number: MFCD00214312 Molecular Formula: C17H19F2N3O3 Molecular Weight: 387.81 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal
Catalog Number:
(101942-768)
Supplier:
Matrix Scientific
Description:
MF=C6H10Cln3 MW=159.62 Cas=6882-74-2 1G
Catalog Number:
(76078-794)
Supplier:
Bioss
Description:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Catalog Number:
(76078-796)
Supplier:
Bioss
Description:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, rac-Clemastine Fumarate EP Impurity B HCl (Mixture of Diastereomers)
Catalog Number:
(EM8.20575.0001)
Supplier:
MilliporeSigma
Description:
2, 7-Fluorenediammonium dichloride for synthesis, Cas Number: 13548-69-1, Synonyms: 2, 7-Diaminofluorene dihydrochloride.
Catalog Number:
(TCB1987-005G)
Supplier:
TCI America
Description:
CAS Number: 30315-46-9
MDL Number: MFCD00190165
Molecular Formula: C7H17NO2
Molecular Weight: 147.22
Purity/Analysis Method: <gt/>96.0% (GC)
Form: Crystal
Melting point (°C): 81
Specific rotation [a]20/D: -29 deg (C=2, 1mol/L HCl)
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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