H-d-Ser(tBu)-OMe·HCl
Supplier:
AMBEED, INC
Description:
Fmoc-Ser(HPO3Bzl)-OH, Purity: 97%, CAS number: 158171-14-3, Appearance: White to yellow powder or crystals, Storage: Inert atmosphere, Room Temperature, Size: 250MG
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
O-Benzyl-L-serine 99%
Supplier:
AMBEED, INC
Description:
1-Methyl-N-carbobenzoxy-L-glutamate 98%
Supplier:
Bachem Americas
Description:
The dipeptide Ser-Pro is obtained from bradykinin by action of angiotensin-converting enzyme (ACE). Substrate for skin fibroblast prolidase.
Catalog Number:
(102546-640)
Supplier:
Matrix Scientific
Description:
MF=C9H17NO4 MW=203.24 CAS=28875-17-4 MDL=MFCD00038513 5G
Catalog Number:
(10411-694)
Supplier:
Bioss
Description:
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at 'Ser-178' and 'Thr-507' and phosphorylation of CDC25C at 'Ser-216' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at 'Ser-76', 'Ser-124', 'Ser-178', 'Ser-279' and 'Ser-293' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at 'Ser-76' primes the protein for subsequent phosphorylation at 'Ser-79', 'Ser-82' and 'Ser-88' by NEK11, which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at 'Thr-309', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates multiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cellular proliferation. Also promotes repair of DNA cross-links through phosphorylation of FANCE. Binds to and phosphorylates TLK1 at 'Ser-743', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance through regulation of PCNA.
Supplier:
Bachem Americas
Description:
Sequence: Boc-D-Ser(Bzl)-OH
Catalog Number:
(BDH7614-4)
Supplier:
VWR International
Description:
Per liter formula:
250 ml ACS HCL 36.5-38% w/w 750 ml deionized water
Supplier:
ACROBIOSYSTEMS INC MS
Description:
Human IL-8 protein, His, Avitag*, Biotinylated, Source: expressed from HEK293. It contains AA Ser 28 - Ser 99, Predicted N-terminus: Ser 28, protein carries a polyhistidine tag at C-terminus, followed by an Avi tag, Synonyms: CXCL8, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, Size: 200uG
Supplier:
AMBEED, INC
Description:
Boc-D-Ser-OH, Purity: 98%, CAS Number: 6368-20-3, Appearance: Form: Crystal - Powder / Colour: White - Very pale yellow, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 10G
Catalog Number:
(103889-084)
Supplier:
ACROBIOSYSTEMS INC MS
Description:
Human SLAMF7 / CRACC / CD319 Protein, His Tag (Site-specific conjugation), PE-Labeled, Source: expressed from HEK293. It contains AA Ser 23 - Met 226, Predicted N-terminus: Ser 23, protein carries polyhistidine tag at the C-terminus, Synonyms: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12, Size: 25tests
Supplier:
Thermo Scientific Chemicals
Description:
N-Benzyloxycarbonylglycine methyl ester, 98%
Catalog Number:
(10401-800)
Supplier:
Bioss
Description:
The Sarco(endo)plasmic-reticulum (SER) regulatory protein, Phospholamban (PLB), is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle. Believed to assemble into a pentamer, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a). Non-phosphorylated PLB associates with SERCA2a, and inhibits Ca2+ reuptake into the SER. PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, Ser-16, Thr-17) are phosphorylated by numerous effectors, which include PKC, PKA, PKG, and CaM kinase. Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, which accelerates ventricular relaxation.
Supplier:
AMBEED, INC
Description:
H-D-Ser(Bzl)-OH, Purity: 97%, CAS Number: 10433-52-0, Appearance: Form: powder Colour: white - light yellow, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100g
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