Indium(III)+phosphate
Catalog Number:
(10454-306)
Supplier:
Bioss
Description:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
Catalog Number:
(10453-922)
Supplier:
Bioss
Description:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
Catalog Number:
(10793-496)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to VEGFR-2 (kinase insert domain receptor (a type III receptor tyrosine kinase))
Catalog Number:
(77439-826)
Supplier:
Bioss
Description:
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Catalog Number:
(77439-824)
Supplier:
Bioss
Description:
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Catalog Number:
(10299-308)
Supplier:
Bioss
Description:
GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Supplier:
BeanTown Chemical
Description:
CAS: 124-43-6; EC No: 204-701-4; MDL No: MFCD00013119
UN No: UN1511; Haz Class: 5.1 (8); Packing Group: III
Crystalline; Linear Formula: CO(NH2)2·H2O2 ; Molecular Formula: CH4N2O·H2O2 ; MW: 94.07
Melting Point: 90-93°
Density (g/mL): 1.39
Air Sensitive, Light Sensitive, Moisture Sensitive
Catalog Number:
(10110-076)
Supplier:
Prosci
Description:
UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme.The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(10102-298)
Supplier:
Prosci
Description:
SIRT5 is included in class III of the sirtuin family which ischaracterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.
Supplier:
BeanTown Chemical
Description:
CAS: 68-12-2; EC No: 200-679-5; MDL No: MFCD00003284; RTECS: LQ2100000
UN No: UN2265; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: HCON(CH3)2 ; Molecular Formula: C3H7NO; MW: 73.09
Melting Point: -61°; Boiling Point: 153°; Flash point: 57°C (135°F)
Density (g/mL): 0.944; Refractive Index: 1.430
Supplier:
BeanTown Chemical
Description:
CAS: 110-80-5; EC No: 203-804-1; MDL No: MFCD00002869; RTECS: KK8050000
UN No: UN1171; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3CH2OCH2CH2OH; Molecular Formula: C4H10O2; MW: 90.12
Melting Point: -90°; Boiling Point: 135°; Flash point: 42°C (108°F)
Density (g/mL): 0.93; Refractive Index: 1.407
Supplier:
BeanTown Chemical
Description:
CAS: 115383-22-7; MDL No: MFCD00282904
UN No: UN1325; Haz Class: 4.1; Packing Group: III
Powder; Molecular Formula: C; MW: 12.011
Catalog Number:
(MSPP-PAA573MU8)
Supplier:
CLOUD-CLONE CORP MS
Description:
Polyclonal antibody to Procollagen III N-Terminal Propeptide (PIIINP), derived from recombinant PIIINP(Gln24~Pro154), is reactive with Mouse/Rat.
Catalog Number:
(76117-480)
Supplier:
Bioss
Description:
NT5C1A dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. It helps to regulate adenosine levels in the heart during ischemia and hypoxia.
Supplier:
BeanTown Chemical
Description:
CAS: 87120-72-7; MDL No: MFCD01076201
UN No: UN3259; Haz Class: 8; Packing Group: III
Solid; Molecular Formula: C10H20N2O2; MW: 200.28
Melting Point: 44-48°
Air Sensitive
Catalog Number:
(10230-256)
Supplier:
Bioss
Description:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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