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Indium(III)+phosphate
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Indium(III)+phosphate
Supplier:
Enzo Life Sciences
Description:
Metallothioneins (MTs) are a class of ubiquitous, low molecular weight, cysteine-rich, metal binding proteins that function in the metabolism of zinc and copper. MT protects against exposure to toxic metals such as mercury and cadmium as well as a variety of other stress conditions. There are four mammalian MT isoforms: MT-I, -II, -III, -IV, each of which is encoded by individual genes. MT expression is induced by heavy metal cations, starvation, elevated temperature, lipopolysaccharide, inflammatory cytokines, free radicals, and ionizing radiation.
Supplier:
BeanTown Chemical
Description:
CAS: 12607-70-4; EC No: 235-715-9; MDL No: MFCD00016262; RTECS: QR6250000
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Linear Formula: NiCO3·2Ni(OH)2·xH2O; MW: 304.11 (anhydrous)
Catalog Number:
(76010-912)
Supplier:
Prosci
Description:
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The transit peptide of the Rieske protein seems to form part of the bc1 complex and is considered to be the subunit 11/IX of that complex (By similarity).
Catalog Number:
(76084-192)
Supplier:
Bioss
Description:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
Catalog Number:
(76100-144)
Supplier:
Bioss
Description:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Supplier:
BeanTown Chemical
Description:
CAS: 10101-97-0; EC No: 232-104-9; MDL No: MFCD00149813; RTECS: QR9600000
UN No: UN3288; Haz Class: 6.1; Packing Group: III
Crystalline/Powder; Linear Formula: NiSO4·6H2O; MW: 262.86
Density (g/mL): 2.070
Catalog Number:
(89367-654)
Supplier:
Genetex
Description:
Rabbit polyclonal to NTH1
Supplier:
Electron Microscopy Sciences
Description:
Perfusion washes and fixatives are ready to use solution which are recommended by the NeuroScience Association.
Supplier:
BeanTown Chemical
Description:
CAS: 623-47-2; EC No: 210-795-8; MDL No: MFCD00009184
UN No: UN3272; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: HC≡CCO2CH2CH3; Molecular Formula: C5H6O2; MW: 98.10
Boiling Point: 120°; Flash point: 25°C (77°F)
Density (g/mL): 0.968; Refractive Index: 1.412
Supplier:
BeanTown Chemical
Description:
CAS: 865-49-6; EC No: 212-742-4; MDL No: MFCD00000827
UN No: UN1888; Haz Class: 6.1; Packing Group: III
Liquid, in prescored ampules, 0.75ml/ampule ; Molecular Formula: CDCl3; MW: 120.38
Melting Point: -64°; Boiling Point: 60.9°
Density (g/mL): 1.5; Refractive Index: 1.444
Light Sensitive, Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 5588-84-1; EC No: 226-997-4; MDL No: MFCD00015017
UN No: UN1993; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: V(O)[OCH(CH3)2]3; Molecular Formula: C9H21O4V; MW: 244.20
Melting Point: -12°; Boiling Point: 80-82°/2 mmHg; Flash point: 45°C (113°F)
Density (g/mL): 1.035; Refractive Index: 1.479
Moisture Sensitive
Catalog Number:
(EM1.08525.0100)
Catalog Number:
(89139-424)
Supplier:
Biotium
Description:
Nerve terminal probes are a series of fluorescent cationic styryl dyes developed to follow synaptic activity
Supplier:
BeanTown Chemical
Description:
CAS: 865-49-6; EC No: 212-742-4; MDL No: MFCD00000827
UN No: UN1888; Haz Class: 6.1; Packing Group: III
Liquid, in prescored ampules, 0.75ml/ampule; Molecular Formula: CDCl3; MW: 120.38
Melting Point: -64°; Boiling Point: 60.9°
Density (g/mL): 1.5; Refractive Index: 1.444
Light Sensitive, Moisture Sensitive
Catalog Number:
(10298-866)
Supplier:
Bioss
Description:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
Catalog Number:
(10233-180)
Supplier:
Bioss
Description:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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