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Isobutyl+isothiocyanate
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Isobutyl+isothiocyanate
Catalog Number:
(10344-216)
Supplier:
Bioss
Description:
May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
Catalog Number:
(10229-134)
Supplier:
Bioss
Description:
Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Catalog Number:
(10458-856)
Supplier:
Bioss
Description:
Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity).
Catalog Number:
(10342-202)
Supplier:
Bioss
Description:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Catalog Number:
(10429-984)
Supplier:
Bioss
Description:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
Catalog Number:
(10462-000)
Supplier:
Bioss
Description:
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Catalog Number:
(10765-244)
Supplier:
Prosci
Description:
The LN3 monoclonal antibody specifically reacts with the human leukocyte antigen-DR (HLA-DR), a MHC class II heterodimeric surface glycoprotein. HLA-DR is expressed on the antigen presenting surfaces of monocytes, macrophages, dendritic cells, activated T cells, and B cells. It is integral to peptide presentation to CD4+ T cells.
Catalog Number:
(115104-BL)
Supplier:
Biolegend
Description:
FITC anti-mouse H-2Kq [KH114]; Isotype: Mouse (BALB/c) IgG2a, κ; Reactivity: Mouse q haplotype, Does not cross-react with other haplotypes (e.g. a, b, d, f, k, n, p, r, s, u, v); Apps: FC; Size: 500 μg
Catalog Number:
(10307-496)
Supplier:
Bioss
Description:
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Supplier:
Biolegend
Description:
FITC anti-human CD62L [DREG-56]; Isotype: Mouse IgG1, κ; Reactivity: Human, Cross-Reactivity: Chimpanzee, Cattle (Bovine, Cow); Apps: FC; Size: 100 μg
Supplier:
Tonbo Biosciences
Description:
The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation.
Catalog Number:
(103294-852)
Supplier:
Novus Biologicals
Description:
The Apolipoprotein E3 / ApoE3 Antibody (960319) [FITC] from Novus Biologicals is a mouse monoclonal antibody to Apolipoprotein E3 / ApoE3. This antibody reacts with human. The Apolipoprotein E3 / ApoE3 Antibody (960319) [FITC] has been validated for the following applications: Western Blot.
Catalog Number:
(10307-466)
Supplier:
Bioss
Description:
Human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD].
Supplier:
Biolegend
Description:
FITC anti-human CD107a (LAMP-1) [H4A3]; Isotype: Mouse IgG1, κ; Reactivity: Human, African Green, Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus; Apps: FC; Size: 100 tests
Supplier:
Biolegend
Description:
FITC anti-human CD127 (IL-7Rα) [A019D5]; Isotype: Mouse IgG1, κ; Reactivity: Human, African Green, Baboon, Cynomolgus, Rhesus; Apps: FC; Size: 100 tests
Supplier:
Biolegend
Description:
FITC anti-human CD51/61 [23C6]; Isotype: Mouse IgG1, κ; Reactivity: Human, African Green, Chicken, Cynomolgus, Rabbit (Lapine); Apps: FC; Size: 100 tests
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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