Lead(II)+oxide
Catalog Number:
(10348-604)
Supplier:
Bioss
Description:
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Catalog Number:
(76196-014)
Supplier:
Prosci
Description:
This mAb reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36kDa) and a beta chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some auto-immune diseases are associated with certain class II alleles.
Catalog Number:
(10663-526)
Supplier:
Bioss
Description:
Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.
Catalog Number:
(14004-178)
Supplier:
Steris
Description:
Cage-Klenz® 250 Detergent is a liquid phosphate-free, citric acid-based detergent.
Catalog Number:
(102513-404)
Supplier:
Adipogen
Description:
CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.
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Supplier:
Adipogen
Description:
Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcription and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells
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Catalog Number:
(10663-534)
Supplier:
Bioss
Description:
Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.
Catalog Number:
(77440-750)
Supplier:
Bioss
Description:
Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a 5-cap motif and recruits the 43S ribosomal preinitiation complex to the eligible transcript. Along with eIF4B, the eIF4F complex mediates the unwinding of mRNA secondary structure to facilitate ribosome association. eIF4E specifically interacts with the 5 cap, eIF4A(I,II) are bidirectional RNA helicases, and eIF4G(I,II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3 and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.
Supplier:
Bachem Americas
Description:
Please see also 5-(Pentafluorobenzoylamino)fluorescein (M-2375), a sensitive fluorogenic substrate for the determination of glutathione S-transferase (GST) activity and glutathione (GSH) concentration, and the carba-analog of GSH, ophthalmic acid, H-3145.
Supplier:
MilliporeSigma
Description:
Clear and free from particulates. Stabilized with 25ppm BHT. Suitable for use in organic synthesis and other anhydrous solvent applications. Elbow adapter with septum cap (EM-692004-2) allows for the removal of solvent under nitrogen atmosphere. Replacement septum (EM-692004S-2), for use with elbow adapter, minimizes air and moisture intrusion once the primary septum is punctured. Drying tube (EM-692010-2) filled with t.h.e.* desiccant indicating silica gel removes solvent under a dry-air atmosphere. Large plug (EM-692012-2) is a replacement plug for bottle top.
Catalog Number:
(62661-502)
Supplier:
Akro-Mils
Description:
Akro-Mils industry leading 4" tall shelf bins are constructed of durable industrial-grade plastic and provide a neat and attractive storage solution.
Catalog Number:
(100243-638)
Supplier:
Southern Biotechnology
Description:
Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.
Catalog Number:
(89495-246)
Supplier:
Simport Scientific
Description:
Pads are used to hold biopsies in place during processing
Catalog Number:
(76314-892)
Supplier:
SLICE, INC.
Description:
This industrial knife is designed specifically for thick materials like foam and fiberglass insulation.
Supplier:
Liveo
Description:
High vacuum grease is ideal for sealing and lubricating vacuum and pressure systems
Supplier:
Plas-Labs
Description:
One-piece Noryl® boards feature quick set-up and release
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