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Methyl+2-amino-3,5-difluorobenzoate
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Methyl+2-amino-3,5-difluorobenzoate
Catalog Number:
(10666-794)
Supplier:
Bioss
Description:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
Catalog Number:
(76120-676)
Supplier:
Bioss
Description:
ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3_5_-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Catalog Number:
(101937-612)
Supplier:
Matrix Scientific
Description:
MF=C6H7Brn2 MW=187.05 Cas=186593-43-1 1G
Catalog Number:
(102539-794)
Supplier:
Matrix Scientific
Description:
MF=C8H9NO2 MW=151.17 CAS=52130-17-3 MDL=MFCD00075026 100G
Supplier:
AMBEED, INC
Description:
4-(1-Hydroxyethyl)aniline, Purity: 98%, CAS Number: 14572-89-5, Appearance: Form: solid Colour: Pale-yellow to Yellow, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 1g
Supplier:
ALADDIN SCIENTIFIC
Description:
Voltammetric behavior of 2-amino-6-nitrobenzothiazole has been investigated using direct current voltammetry and differential pulse voltammetry2-Amino-6-nitrobenzothiazole has been used: . as model analyte for voltammetric determination of electrochemically reducible organic substances[4] . in the synthesis of 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid[2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide derivatives . in the preparation of push-pull nonlinear optical chromophores containing thiazole and benzothiazole acceptors . as a base in dye production by diazotation reaction
Supplier:
TCI America
Description:
CAS Number: 951-55-3
MDL Number: MFCD00005652 Molecular Formula: C12H14N2O2 Molecular Weight: 218.26 Purity/Analysis Method: >98.0% (T,HPLC) Form: Crystal Melting point (°C): 275 Specific rotation [a]20/D: 0 deg (C=1, HCl)
Supplier:
Thermo Scientific Chemicals
Description:
3-Amino-4-fluorotoluene 6-Fluoro-m-toluidine. Grade: 98. Melting Point C. Boiling Point C: 80-86*/11mm. C7H8FN. 452-84-6. HARMFUL IRRITANT
Supplier:
AMBEED, INC
Description:
Bisacrylamide 97%
Catalog Number:
(10480-550)
Supplier:
Bioss
Description:
DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044192-5G , MDL Number: MFCD00027378
Catalog Number:
(75788-736)
Supplier:
Prosci
Description:
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa extracellular domain (ECD) with one Ig-like V-type domain, a 21 aa transmembrane (TM) sequence, and a 41 aa cytoplasmic sequence.It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Catalog Number:
(76066-194)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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