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Methyl+3,5-dimethyl-4-propoxybenzoate
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Methyl+3,5-dimethyl-4-propoxybenzoate
Catalog Number:
(10429-674)
Supplier:
Bioss
Description:
Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates. Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a. H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3). Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53. Repression of TP53 blocks cellular senescence (By similarity). Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity. Methylates HMGA1. Regulates alternative splicing events. Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7 (NC).
Catalog Number:
(102991-276)
Supplier:
Adipogen
Description:
CD14/TLR4 antagonist. Inhibitor of sterile inflammation. Synthetic TLR4/CD14 ligand with TLR4 modulating activities in vitro, and conferring protection against TLR4/CD14-mediated tissue damage and inflammation in vivo. Useful to explore CD14- dependent and TLR4-independent pathways and TLR4 activation by endogenous ligands (e.g. hyaluronic acid oligosaccharides, oxLDL, HMGB1) in sterile inflammation. Shown to inhibit neuropathic pain, secondary necrosis of acute drug-induced liver failure and vascular inflammation, and abdominal aortic aneurysm by blocking non-hematopoietic TLR4 signaling. Useful tool, where inhibition of sterile (auto-) inflammation is desired, without compromising TLR4’s key role in the defense of pathogens.
Catalog Number:
(101920-640)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 060765-500MG , MDL Number: MFCD18071330
Catalog Number:
(101921-868)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 061387-500MG , MDL Number: MFCD06127499
Catalog Number:
(77258-436)
Supplier:
AMBEED, INC
Description:
N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide, Purity: 97%, CAS Number: 1702259-66-2, Appearance: White to Yellow Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 1mg
Catalog Number:
(101830-042)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 030390-500MG , MDL Number: MFCD01940414
Supplier:
AOB CHEM USA
Description:
2-Methoxy-4-methyl-5-pyridineboronic acid ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 045087-1G , MDL Number: MFCD01102674
Supplier:
AMBEED, INC
Description:
4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile 95%
Supplier:
TCI America
Description:
Sisomicin Sulfate, Purity: >98.0%(HPLC), CAS number: 53179-09-2, Molecular Formula: C19H37N5O7.21/2H2SO4, Molecular Weight: 692.71, Size: 250MG
Catalog Number:
(101827-414)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 029070-500MG , MDL Number: MFCD03075018
Catalog Number:
(102669-908)
Supplier:
Matrix Scientific
Description:
5-Allyl-6-methyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one
Catalog Number:
(101816-440)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 023660-500MG , MDL Number: MFCD08688185
Catalog Number:
(100504-578)
Supplier:
Electron Microscopy Sciences
Description:
Crystal Violet Stain for Amyloid, Stain results - Amyloid: Violet-Red, Tissue: Blue
Supplier:
Matrix Scientific
Description:
2-[4-Chloro-3-(difluoromethyl)-5-methyl-1H-pyrazol-1-yl]propanoic acid
Catalog Number:
(80601-362)
Supplier:
MilliporeSigma
Description:
Pravastatin, Sodium Salt, a water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Káµ¢ = ~1 nM).
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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