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Methyl-3-(1H-pyrazol-1-yl)benzoate
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Methyl-3-(1H-pyrazol-1-yl)benzoate
Catalog Number:
(101929-154)
Supplier:
Matrix Scientific
Description:
MF=C10H10N4O2 MW=218.22 MDL=MFCD11108893 500Mg
Supplier:
Adipogen
Description:
Antagonizing the Chk1-mediated cell cycle checkpoints has emerged as an attractive target for anticancer therapy. If Chk1 activity is blocked, DNA-damaged or spindle-disrupted cells would exit cell cycle arrest before full repair and subsequently undergo mitotic catastrophe or cell death. Chk1 inhibitors consequently increase the therapeutic index of DNA-damaging or antimitotic agents as well. PF-0477736 is a selective, potent ATP-competitive Chk1 inhibitor, derived from PF-0394691, inhibits Chk1 (Ki, 0.49nM) and Chk2 (Ki, 47nM) in vitro. In tests, PF-0477736 was identified as a potent, selective ATP-competitive small-molecule inhibitor that inhibits Chk1 with a Ki of 0.49nM. PF-0477736 abrogates cell cycle arrest induced by DNA damage and enhances cytotoxicity of clinically important chemotherapeutic agents, including gemcitabine and carboplatin. In xenografts, PF-0477736 enhanced the antitumor activity of gemcitabine in a dose-dependent manner. PF-0477736 combinations were well tolerated with no exacerbation of side effects commonly associated with cytotoxic agents.
Catalog Number:
(101842-894)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 037204-500MG , MDL Number: MFCD03196939
Supplier:
Thermo Scientific Chemicals
Description:
25g CAS: 152120-54-2, MDL: MFCD01075122
Catalog Number:
(76814-500)
Supplier:
AMBEED, INC
Description:
Ethyl 2-(1H-imidazol-1-yl)benzoate, Purity: 95%, CAS Number: 117296-92-1, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Supplier:
AMBEED, INC
Description:
tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate 97%
Supplier:
Matrix Scientific
Description:
MF=C14H22N4O4 MW=310.36 CAS=152120-54-2 MDL=MFCD01075122 5G
Catalog Number:
(76997-766)
Supplier:
AMBEED, INC
Description:
Ethyl 4-(1H-1,2,4-triazol-1-yl)benzoate, Purity: 97%, CAS number: 143426-48-6, Appearance: White to yellow powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 1G
Catalog Number:
(101896-880)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 051747-500MG , MDL Number: MFCD13561782
Catalog Number:
(101931-702)
Supplier:
Matrix Scientific
Description:
MF=C15H15No4 MW=273.29 MDL=MFCD03620181 500Mg
Catalog Number:
(101931-700)
Supplier:
Matrix Scientific
Description:
MF=C13H11No4 MW=245.24 Cas=14794-06-0 MDL=MFCD00022580 ,500Mg
Supplier:
BeanTown Chemical
Description:
CAS: 152120-54-2; MDL No: MFCD01075122
Solid; Molecular Formula: C14H22N4O4 ; MW: 310.35
Melting Point: 86-90°
Catalog Number:
(101930-480)
Supplier:
Matrix Scientific
Description:
MF=C19H15No2S3 MW=385.53 MDL=MFCD01960201 ,500Mg
Supplier:
Matrix Scientific
Description:
Methyl-4-((3-methylpiperazin-1-yl)methyl)benzoate 95
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064082-1G , MDL Number: MFCD06105406
Supplier:
AMBEED, INC
Description:
2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate 95%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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