Text Search >
N-Octanoyl-L-homoserine+lactone
Print…
You Searched For:
1,590 results were found
N-Octanoyl-L-homoserine+lactone
Supplier:
Bachem Americas
Description:
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). Recently, ghrelin ("ghre" is the Proto-Indo-European root of the word "grow") has been identified as an endogenous ligand for GHS-R. These peptides consist of 28 amino acids with an octanoyl-residue at Ser³, which is essential for expressing activity. Ghrelin stimulates GH release from rat primary culture pituitary cells in a dose-dependent manner and induces an increase in intracellular Ca²⁺ in GHS-R-expressing cells with an EC₅₀ value of 2.5 nM. Human ghrelin is homologous to rat ghrelin apart from two amino acids. The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelin. In future, ghrelin might be used in the treatment of aging patients as well as in patients with idiopathic GH deficiency, obesity, osteoporosis or cardiovascular diseases.
Catalog Number:
(103005-290)
Supplier:
Anaspec Inc
Description:
This Ghrelin peptide is biotinylated at the peptide N-terminus. Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.
Sequence: Biotin-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR MW: 3597.2 Da % Peak area by HPLC: 95 Storage condition: -20° C
Supplier:
Spectrum Chemicals
Description:
Caprylic/Capric Triglyceride is a medium-chain triglyceride used as a component of ointments, creams, and liquid emulsions.
Catalog Number:
(AAJ65946-EXD)
Supplier:
Thermo Scientific Chemicals
Description:
CAS No.: 313951-59-6
Molecular Formula: C141H235N47O41 Formula Weight: 3244.66 Storage Temperature: -30°C to -10°C Physical Form: Solid Appearance: White to off-white MDL No.: MFCD08460342
Catalog Number:
(76011-782)
Supplier:
Prosci
Description:
MBOAT4 mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.
Supplier:
Matrix Scientific
Description:
L-Homoserine ≥95%
Catalog Number:
(EM8.14359.0001)
Supplier:
MilliporeSigma
Supplier:
Anaspec Inc
Description:
Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin, also known as acyl-Ghrelin (AG), is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.
Sequence: GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR MW: 3370.9 Da % Peak area by HPLC: 95 Storage condition: -20° C
Catalog Number:
(102528-274)
Supplier:
Matrix Scientific
Description:
MF=C4H9NO3 MW=119.12 CAS=6027-21-0 MDL=MFCD00077786 5G
Supplier:
TCI America
Description:
CAS Number: 6027-21-0
MDL Number: MFCD00077786 Molecular Formula: C4H9NO3 Molecular Weight: 119.12 Purity/Analysis Method: >96.0% (T) Form: Crystal Melting point (°C): 204 Specific rotation [a]20/D: 8 deg (C=2, H2O)
Supplier:
Bachem Americas
Description:
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary through a G protein-coupled receptor (GHS-R). Recently, ghrelin ("ghre" is the Proto-Indo-European root of the word "grow") has been identified as an endogenous ligand for GHS-R. These peptides consist of 28 amino acids with an octanoyl-residue at Ser³, which is essential for expressing activity. Ghrelin stimulates GH release from rat primary culture pituitary cells in a dose-dependent manner and induces an increase in intracellular Ca²⁺ in GHS-R-expressing cells with an EC₅₀ value of 2.5 nM. Human ghrelin is homologous to rat ghrelin apart from two amino acids. The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelin. In future, ghrelin might be used in the treatment of aging patients as well as in patients with idiopathic GH deficiency, obesity, osteoporosis or cardiovascular diseases.
Supplier:
Thermo Scientific Chemicals
Description:
L-2-Amino-4-hydroxybutyric acid H-Hser-OH. Grade:99, Melting Point ca 203*[degree]C. Boiling Point C:NA. C4H9NO3. 672-15-1.
Catalog Number:
(TS20476-0050)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
DL-Homoserine 99%
Supplier:
AMBEED, INC
Description:
Boc-d-homoserine 95%
Supplier:
Anaspec Inc
Description:
Rat/mouse Ghrelin differs from human Ghrelin on the 11th and 12th position - RV (Arg-Val) in rat/mouse and KA (Lys-Ala) in human. Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.
Sequence: GS-S(n-octanoyl)-FLSPEHQKAQQRKESKKPPAKLQPR MW: 3314.8 Da % Peak area by HPLC: 95 Storage condition: -20° C
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||
List View
