Nickel(II)+p-toluenesulfonate
Catalog Number:
(76085-486)
Supplier:
Bioss
Description:
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Catalog Number:
(10331-434)
Supplier:
Bioss
Description:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Catalog Number:
(10077-766)
Supplier:
Prosci
Description:
CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease.
Supplier:
BeanTown Chemical
Description:
CAS: 122-18-9; EC No: 204-526-3; MDL No: MFCD00011625; RTECS: BO6822450
UN No: UN3261; Haz Class: 8; Packing Group: II
Powder; Molecular Formula: C25H46ClN·xH2O; MW: 396.09 (anhydrous)
Catalog Number:
(76011-482)
Supplier:
Prosci
Description:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.
Supplier:
BeanTown Chemical
Description:
CAS: 40400-13-3; MDL No: MFCD00236046
UN No: UN3261; Haz Class: 8; Packing Group: II
Solid; Molecular Formula: C7H6BrI; MW: 296.93
Melting Point: 54-60°
Light Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 58757-38-3; MDL No: MFCD00051775
UN No: UN3261; Haz Class: 8; Packing Group: II
Crystalline/Powder; Molecular Formula: C6H3Cl2NO; MW: 176.00
Melting Point: 48-53°
Moisture Sensitive
Supplier:
MP Biomedicals
Description:
Boric acid is used for weatherproofing wood and fireproofing fabrics; as a preservative; manufacturing of cements, crockery, porcelain, enamels, glass, borates, leather, carpets, hats, soaps, artificial gems; in nickeling baths; cosmetics; printing and dyeing, painting; photography; for impregnating wicks; electric condensers; hardening steel. It is also used as an insecticide for cockroaches and black carpet beetles. It is used In the research labs , astringent, antiseptic, antibacterial and antifungal agent. It is used in buffers and for calibration of polyacrylamide gel columns for the separation of oligonucleotides by capillary electrophoresis.
Supplier:
Biotium
Description:
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number:
(103321-844)
Supplier:
Novus Biologicals
Description:
The Annexin A2 Antibody (1G7) from Novus Biologicals is a mouse monoclonal antibody to Annexin A2. This antibody reacts with human, mouse. The Annexin A2 Antibody (1G7) has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry / Immunofluorescence.
Catalog Number:
(103307-762)
Supplier:
Novus Biologicals
Description:
The POLR2J Antibody (1A10) from Novus Biologicals is a mouse monoclonal antibody to POLR2J. This antibody reacts with human. The POLR2J Antibody (1A10) has been validated for the following applications: Western Blot, ELISA.
Catalog Number:
(10802-564)
Supplier:
Rockland Immunochemical
Description:
Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
Supplier:
BeanTown Chemical
Description:
CAS: 7790-99-0; EC No: 232-236-7; MDL No: MFCD00011354
UN No: UN2920; Haz Class: 8 (3); Packing Group: II
Liquid; Linear Formula: ICl; MW: 162.36
Light Sensitive, Moisture Sensitive
Catalog Number:
(76196-088)
Supplier:
Prosci
Description:
PAX6 is a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [RefSeq]
Catalog Number:
(76194-380)
Supplier:
Prosci
Description:
Recognizes proteins of 33, 35 and 41kDa, which are identified as various isoforms of CD74/CLIP. Its epitope is localized in the extracellular domain of CD74. CD74/CLIP is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74/CLIP is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. It is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74/CLIP stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas and has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
Catalog Number:
(75935-514)
Supplier:
Rockland Immunochemical
Description:
The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment.
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