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Pentafluorophenyl+isothiocyanate
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Pentafluorophenyl+isothiocyanate
Catalog Number:
(10426-136)
Supplier:
Bioss
Description:
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Catalog Number:
(10424-022)
Supplier:
Bioss
Description:
ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Catalog Number:
(10430-780)
Supplier:
Bioss
Description:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Overexpression may be associated with abnormal proliferation in human breast tissue.
Catalog Number:
(10451-308)
Supplier:
Bioss
Description:
Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Catalog Number:
(10427-386)
Supplier:
Bioss
Description:
Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).
Catalog Number:
(10461-014)
Supplier:
Bioss
Description:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Catalog Number:
(10352-168)
Supplier:
Bioss
Description:
FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
Catalog Number:
(10477-480)
Supplier:
Bioss
Description:
This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, adevelopmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008].
Catalog Number:
(10407-406)
Supplier:
Bioss
Description:
FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids from precursor essential polyunsaturated fatty acids, linoleic acid and alphanlinolenic acid. It catalyzes the desaturation of dihomo gamma linoleic acid and eicosatetraenoic acid to generate arachidonic acid and eicosapentaenoic acid respectively.
Catalog Number:
(10663-940)
Supplier:
Bioss
Description:
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
Supplier:
Biolegend
Description:
FITC anti-mouse Ly-6G/Ly-6C (Gr-1) [RB6-8C5]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC; Size: 500 μg
Catalog Number:
(103265-212)
Supplier:
Southern Biotechnology
Description:
FITC Anti-Human IgE Fc antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number:
(10267-554)
Supplier:
Bioss
Description:
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Catalog Number:
(102125-740)
Supplier:
Novus Biologicals
Description:
The Endoglin / CD105 Antibody (MEM-229) [FITC] from Novus Biologicals is a mouse monoclonal antibody to Endoglin / CD105. This antibody reacts with human, porcine. The Endoglin / CD105 Antibody (MEM-229) [FITC] has been validated for the following applications: Flow Cytometry.
Catalog Number:
(10304-570)
Supplier:
Bioss
Description:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Catalog Number:
(103368-206)
Supplier:
Novus Biologicals
Description:
The EGLN3 / PHD3 Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to EGLN3 / PHD3. This antibody reacts with human, mouse, rat. The EGLN3 / PHD3 Antibody [FITC] has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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