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Pyrido[2,3-d]pyrimidin-4(1H)-one
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Pyrido[2,3-d]pyrimidin-4(1H)-one
Catalog Number:
(101836-092)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 033646-500MG , MDL Number: MFCD11049200
Catalog Number:
(76824-252)
Supplier:
AMBEED, INC
Description:
4,4'-(6-Chloropyrimidine-2,4-diyl)dimorpholine, Purity: 95%, CAS Number: 10244-24-3, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 1G
Supplier:
Adipogen
Description:
Potent protein kinase VEGFR2 inhibitor (2nm range). Binds to the pseudokinase domain of MLKL and blocks cell death by necroptosis, as well. With regards to its role in necroptosis, it is an ATP-mimetic that was shown to bind recombinant mouse MLKL pseudokinase domain, which showed inhibited TSQ-induced death of mouse dermal fibroblasts by delaying MLKL translocation to the membrane. Appears therefore to be a valuable reagent to inhibit necroptosis. It also provides an important proof-of-principle that targeting catalytically-dead pseudoenzymes represents a feasible, emerging therapeutic avenue.
Catalog Number:
(101934-266)
Supplier:
Matrix Scientific
Description:
MF=C10H16Cl2N4O MW=279.17 ,250Mg
Catalog Number:
(101934-268)
Supplier:
Matrix Scientific
Description:
MF=C11H18Cl2N4O MW=293.20 ,250Mg
Catalog Number:
(101933-736)
Supplier:
Matrix Scientific
Description:
MF=C12H17Cl2N5O MW=318.21 ,250Mg
Catalog Number:
(101935-292)
Supplier:
Matrix Scientific
Description:
MF=C14H24Cl2N4O MW=335.28 ,250Mg
Catalog Number:
(101935-276)
Supplier:
Matrix Scientific
Description:
MF=C14H24Cl2N4O MW=335.28 ,250Mg
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 14394-61-7, MDL: MFCD00462111
Supplier:
Enzo Life Sciences
Description:
Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.
Supplier:
Adipogen
Description:
GNE-493 is a potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor for the treatment of cancer.
Supplier:
Matrix Scientific
Description:
MF=C11H18BN3O2 MW=235.10 CAS=944401-55-2 MDL=MFCD18072554 5G
Catalog Number:
(200064-436)
Supplier:
New England Biolabs (NEB)
Description:
T4 PDG (pyrimidine dimer glycosylase) has both DNA glycosylase and AP-lyase activity
Catalog Number:
(10108-574)
Supplier:
Prosci
Description:
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Catalog Number:
(102667-026)
Supplier:
Matrix Scientific
Description:
2-Chloro-5-fluoro-4-piperidin-1-ylpyrimidine
Catalog Number:
(77418-744)
Supplier:
APOLLO SCIENTIFIC
Description:
2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinol
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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