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Pyrido[2,3-d]pyrimidin-4(1H)-one
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Pyrido[2,3-d]pyrimidin-4(1H)-one
Catalog Number:
(101935-786)
Supplier:
Matrix Scientific
Description:
MF=C10H17Cl2N3 MW=250.17 250Mg
Supplier:
Adipogen
Description:
BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC(50) values ranging from submicromolar amounts (0.368µM to greater than 450µM.
Catalog Number:
(10108-694)
Supplier:
Prosci
Description:
DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 045183-1G , MDL Number: MFCD01940444
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 048155-5G , MDL Number: MFCD01927046
Supplier:
AMBEED, INC
Description:
Olmutinib 98%
Supplier:
APOLLO SCIENTIFIC
Description:
6-Chloro-N4-methylpyrimidine-2,4-diamine
Supplier:
Enzo Life Sciences
Description:
Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).
Supplier:
Adipogen
Description:
TAK-285 is a novel investigational dual HER2/EGFR inhibitor with IC(50) values of 17 and 23nM, respectively.
Catalog Number:
(101934-824)
Supplier:
Matrix Scientific
Description:
MF=C20H25Brfn5O3 MW=482.36 ,250Mg
Supplier:
APOLLO SCIENTIFIC
Description:
4-Chloro-6-morpholin-4-ylpyrimidin-2-ylamine
Catalog Number:
(10108-692)
Supplier:
Prosci
Description:
DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Supplier:
Thermo Scientific Chemicals
Description:
Stimulates ATP-activated potassium channels
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 053227-500MG , MDL Number: MFCD03669655
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 045673-1G , MDL Number: MFCD03001297
Supplier:
Adipogen
Description:
Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC(50) values of 0.6µM, 0.1µM and 0.1µM, respectively.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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