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Supplier:
TCI America
Description:
CAS Number: 10017-11-5
MDL Number: MFCD00054329 Molecular Formula: C3H7N Molecular Weight: 93.55 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 106
Supplier:
ALADDIN SCIENTIFIC
Description:
3-Amino-2-chloropyridine 98
Supplier:
AOB CHEM USA
Description:
2-Amino-5-phenylpyridine 97
Supplier:
Thermo Scientific Chemicals
Description:
D-Leucine methyl ester hydrochloride, 98%
Catalog Number:
(TCP0561-100G)
Supplier:
TCI America
Description:
CAS Number: 58-56-0
MDL Number: MFCD00012807 Molecular Formula: C8H11NO3 Molecular Weight: 205.64 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 207
Catalog Number:
(101842-168)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 036832-500MG , MDL Number: MFCD12026996
Catalog Number:
(TCD1899-100G)
Supplier:
TCI America
Description:
CAS Number: 6638-79-5
MDL Number: MFCD00012485 Molecular Formula: C2H7NO Molecular Weight: 97.54 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 115
Supplier:
AMBEED, INC
Description:
4-Amino-3-bromophenol 97%
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Catalog Number:
(101934-486)
Supplier:
Matrix Scientific
Description:
2-(4-Amino-Pyrazol-1-Yl)-N-(4-Fluoro-Phenyl)-Acetamide Hydrochloride, MF=C11H12Clfn4O MW=270.70 250Mg
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Amino-5-fluorobenzamide 97
Catalog Number:
(101822-594)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 026625-500MG , MDL Number: MFCD09997679
Supplier:
AMBEED, INC
Description:
2-Amino-4-chlorobenzaldehyde 97%
Supplier:
AMBEED, INC
Description:
2-Amino-5-iodopyridine 97%
Supplier:
AMBEED, INC
Description:
5-Amino-6-bromoquinoline 98%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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