(2-Morpholinophenyl)methanol
Supplier:
ALADDIN SCIENTIFIC
Description:
Azide/azido functionalized polyethylene glycol (N3-PEG-X) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials. Azide group can react with alkyne in aqueous solution catalyzed by copper. It can also be reduced into amine group easily while another functional group can be react with other molecules or functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Catalog Number:
(ALA163293100MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
Azide/azido functionalized polyethylene glycol (N3-PEG-X) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials. Azide group can react with alkyne in aqueous solution catalyzed by copper. It can also be reduced into amine group easily while another functional group can be react with other molecules or functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Supplier:
Electron Microscopy Sciences
Description:
TFM™ is an embedding matrix for frozen sections with an ultra pure formulation of water-soluble glycols and resins that provides a solid bond between the tissue and the object holder.
Supplier:
Matrix Scientific
Description:
2-(2-(2-Aminoethoxy)ethoxy)ethanol, Purity: 95+%, CAS Number: 6338-55-2, Molecular Formula: C6H15NO3, Molecular Weight: 149.19, Size: 1G
Catalog Number:
(75835-446)
Supplier:
Restek
Description:
The european pharmacopoeia/ICH Class 2 mix C consists of six components, they are 2-ethoxyethanol (160 μg/ml), ethylene glycol (620 μg/ml), formamide (220 μg/ml), 2-methoxyethanol (methyl cellosolve) (50 μg/ml), n-methylpyrrolidone (4,840 μg/m)l and sulpholane (160 μg/m)l.
Catalog Number:
(102979-288)
Supplier:
Adipogen
Description:
Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage. In comparison with 8-hydroxy-2'-deoxyguanosine (8-OHdG), which is the best known DNA oxidation product it was shown that in a lipopolysaccharide (LPS)-treated mouse liver, 8-OHdG can be stained within 24 hours after LPS treatment. TG can be detected within 6 hours, and remains at least for 72 hours.
Supplier:
ALADDIN SCIENTIFIC
Description:
Azide/azido functionalized polyethylene glycol (N3-PEG-X) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials. Azide group can react with alkyne in aqueous solution catalyzed by copper. It can also be reduced into amine group easily while another functional group can be react with other molecules or functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Supplier:
MP Biomedicals
Description:
Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Supplier:
AMBEED, INC
Description:
t-Boc-N-Amido-PEG7-Amine ≥98%
Supplier:
MP Biomedicals
Description:
Storage: Room Temperature
2-Mercaptoethanol is a hybrid of ethylene glycol and 1,2-ethanedithiol. It is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. It is widely used because the hydroxyl group confers solubility in water and lowers the volatility. Due to its diminished vapor pressure, its odour, while unpleasant, is less objectionable than related thiols. 2-Mercaptoethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis (typically used in SDS-PAGE sample buffer at 5% concentration). Also it reduces excess oxidative polymerization of catalysts. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure. In solution, 2-mercaptoethanol is readily oxidized in air to a disulfide, especially at alkaline pH. Because of this property, it is widely used to protect proteins, enzymes in particular, from becoming inactive. An excess of 2-mercaptoethanol (generally used at 0.01 M) will maintain the protein thiol groups in their reduced state.
Catalog Number:
(700012-434)
Supplier:
Spectrum Chemicals
Description:
Brij(R) S10 is a polyoxyethylene fatty ether derived from stearyl alcohols designed to emulsify and produce stable dispersions of cosmetic materials. It appears as a white, waxy solid.
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Catalog Number:
(EM8.14737.1000)
Catalog Number:
(ALA163289100MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
Azide/azido functionalized polyethylene glycol (N3-PEG-X) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials. Azide group can react with alkyne in aqueous solution catalyzed by copper. It can also be reduced into amine group easily while another functional group can be react with other molecules or functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Catalog Number:
(TCB0955-005ML)
Supplier:
TCI America
Description:
CAS Number: 5451-72-9
MDL Number: MFCD00059371 Molecular Formula: C11H14O3 Molecular Weight: 194.23 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 261 Specific Gravity (20/20): 1.06
Catalog Number:
(TS21945-0500)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(±)-2-Methyl-2,4-pentanediol 99+%
Supplier:
TCI America
Description:
CAS Number: 59551-75-6
MDL Number: MFCD01321130 Molecular Formula: C6H13BrO2 Molecular Weight: 197.07 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Storage Temperature: 0-10°C
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