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2-[(4-Pyridinylmethyl)amino]isonicotinic+acid
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2-[(4-Pyridinylmethyl)amino]isonicotinic+acid
Catalog Number:
(76334-884)
Supplier:
GFG INSTRUMENTATION, INC.
Description:
The IR 29 i is the first intrinsically safe IR gas transmitter with patented GfG 4-beam 4-wavelength technology. Because the IR 29 i is intrinsically safe, there is no need to run transmitter cabling through expensive explosion proof conduit.
Supplier:
Adipogen
Description:
Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta). PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation.
Supplier:
MP Biomedicals
Description:
Evans Blue used in double-labeling procedure for studying axonal branching.
Supplier:
Honeywell Research Chemicals
Description:
2-Ethoxyethanol, Purity: 99%, Grade: Reagent, Cas number: 110-80-5, Molar mass: 90.12 g/mol, Synonyms: Cellosolve(R), Ethyl glycol, Ethylene glycol monoethyl ether, General Purpose Reagent, Performance Grade Solvent, Size: 2.5L
Supplier:
Adipogen
Description:
R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .
Catalog Number:
(10075-446)
Supplier:
Prosci
Description:
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gamma;s, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. It has recently been suggested that PKCepsilon regulates the sensitivity of GABAA alpha1beta2gamma2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of gamma2 (Qi et al., 2007)
Supplier:
MP Biomedicals
Description:
Storage: +4 °C
D-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous tumors than in normal tissues. It is inactivated by binding to avidin. D-Biotin may be used to elute proteins from avidin/streptavidin resins. It is widely used for dietary supplements and fortified foods. It is also used for tablets and hard-shell capsule preparation due to its pharmaceutical properties. Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide. Soluble in water (22 mg/100 mL), ethanol (80 mg/100 mL), more soluble in hot water and in dilute alkalies; insoluble in other common organic solvents. Soluble in 2 M Ammonium hydroxide (50 mg/mL - clear, colorless solution), dimethylformamide (1.7 mg/mL).
Catalog Number:
(101319-572)
Supplier:
Teknova
Description:
Chloramphenicol is a broad-spectrum antibiotic effective against most strains of Gram-positive and Gram-negative bacteria. It is bacteriostatic but may be bactericidal at high concentrations and is lipid-soluble, allowing it to diffuse through the bacterial cell membrane.
Supplier:
Adipogen
Description:
Tandutinib inhibits the auto-phosphorylation of FLT3 (FMS-Like Tyrosine kinase-3, IC(50) of 0.22µM), c-KIT and PDGF (platelet-derived growth factor), thereby inhibiting cellular proliferation and inducing apoptosis.
Supplier:
TCI America
Description:
CAS Number: 110-73-6
MDL Number: MFCD00002841 Molecular Formula: C4H11NO Molecular Weight: 89.14 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 169 Melting point (°C): -90 Flash Point (°C): 71 Specific Gravity (20/20): 0.92
Catalog Number:
(76325-056)
Supplier:
GE Healthcare - Life Sciences
Description:
Novel core bead technology and multimodal ligand give Capto Core 400 dual functionality, size exclusion and binding chromatography, in one chromatography resin.
Supplier:
BeanTown Chemical
Description:
CAS: 115-20-8; EC No: 204-071-0; MDL No: MFCD00004677; RTECS: KM3850000
Liquid; Linear Formula: Cl3CCH2OH ; MW: 149.40
Melting Point: 17.8°; Boiling Point: 152-154°; Flash point: 110°C (230°F)
Density (g/mL): 1.56; Refractive Index: 1.49
Hygroscopic
Supplier:
Ricca Chemical
Description:
Xylenol orange indicator 0.2% (w/v) in alcohol
Supplier:
Adipogen
Description:
PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with an IC(50) of 31nM.
Supplier:
Adipogen
Description:
TG-89 is a JAK inhibitor. It has IC(50) values of 6, 25, 17 and 169nM against JAK2, FLT3, RET and JAK3 respectively.
Supplier:
Adipogen
Description:
Used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. Inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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