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trans-2-Phenylcyclopropylamine+hydrochloride
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trans-2-Phenylcyclopropylamine+hydrochloride
Catalog Number:
(77019-614)
Supplier:
AMBEED, INC
Description:
6-Methyl-1,2,3,4-tetrahydro-isoquinoline hydrochloride 95%
Supplier:
AMBEED, INC
Description:
2-(Pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride, Purity: 98%, CAS Number: 942425-68-5, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 5mg
Catalog Number:
(77165-218)
Supplier:
AMBEED, INC
Description:
(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)methanamine hydrochloride, Purity: 96%, CAS Number: 1364677-67-7, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Supplier:
AMBEED, INC
Description:
2,7-Diazaspiro[4.5]decan-1-one hydrochloride 97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050183-500MG , MDL Number: MFCD13560584
Catalog Number:
(10397-446)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(10397-452)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(10397-450)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(80053-414)
Supplier:
MilliporeSigma
Description:
More soluble analog of arginine and a competitive, slowly reversible inhibitor of endothelial nitric oxide synthase (IC50 = 500nM). CAS: 51298-62-5. FW: 269.7. Purity: >=99% by TLC. Soluble in water. 100mg off-white solid.
Supplier:
APOLLO SCIENTIFIC
Description:
Ethyl-3-(trifluoromethyl)crotonate 97%
Supplier:
Matrix Scientific
Description:
MF=C10H11Brclns MW=292.63 Cas=22964-00-7 5G
Supplier:
AMBEED, INC
Description:
3-Amino-5-hydroxybenzoic acid hydrochloride 97%
Catalog Number:
(101804-548)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 016337-500MG , MDL Number: MFCD05864747
Catalog Number:
(TCH0752-025G)
Supplier:
TCI America
Description:
CAS Number: 1476-98-8
MDL Number: MFCD00135598 Molecular Formula: C20H26N2O2 Molecular Weight: 362.90 Purity/Analysis Method: >98.0% (T,HPLC) Form: Crystal Specific rotation [a]20/D: 188 deg (C=1.3, H2O)
Supplier:
AMBEED, INC
Description:
L-Phenylalanine benzyl ester hydrochloride 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052747-100G , MDL Number: MFCD00013008
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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