trans-4-Aminocyclohexanecarboxylic+acid+hydrochloride
Supplier:
Thermo Scientific Chemicals
Description:
Cytosine deoxyriboside hydrochloride 1-(2-Deoxy-beta-D-ribofuranosyl)cytosine hydrochloride. Grade: 99. Melting Point C168-170*. Boiling Point C: NA. C9H14ClN3O4. 3992-42-5. HYGROSCOPIC
Supplier:
Matrix Scientific
Description:
3-Methylthio-Azetidine Hydrochloride, MF=C4H10Clns MW=139.65 CAS: 179337-60-1 500Mg
Supplier:
AMBEED, INC
Description:
Piperidin-3-one hydrochloride hydrate 97%
Supplier:
AMBEED, INC
Description:
Ethyl-2-hydrazinylacetate hydrochloride 97%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Isonicotinoyl chloride hydrochloride 97%
Supplier:
TCI America
Description:
(R)-3-Methylmorpholine Hydrochloride, Purity: >98.0%(T), CAS number: 953780-78-4, Molecular Formula: C5H11NO.HCl, Molecular Weight: 137.61, Form: Crystal - Powder, White - Pale yellow, Size: 1G
Catalog Number:
(TS46267-0050)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Cyproheptadine hydrochloride sesquihydrate
Catalog Number:
(TCQ0050-1G)
Supplier:
TCI America
Description:
Quinuclidine Hydrochloride, Purity: >98.0%(T), CAS Number: 39896-06-5, Molecular Formula: C7H13N.HCl, Molecular Weight: 147.65, Synonyms: 1-Azabicyclo[2.2.2]octane Hydrochloride, Size: 1G
Catalog Number:
(EM8.18444.0025)
Supplier:
MilliporeSigma
Description:
2-(4-Hydroxyphenyl)ethylammonium chloride, cas number: 60-19-5, Chemical Formula: C8H11NO * HCl, Synonyms: 4-(2-Aminoethyl)phenol hydrochloride, Tyramine hydrochloride, for synthesis, 25g
Catalog Number:
(10397-450)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(10397-446)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Catalog Number:
(89141-386)
Supplier:
Enzo Life Sciences
Description:
Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.
Supplier:
Matrix Scientific
Description:
MF=C5H12CLNO MW=137.61 CAS=1184919-69-4 MDL=MFCD16619116 1G
Supplier:
AMBEED, INC
Description:
2-Iminothiolane hydrochloride, Purity: 95%, CAS Number: 4781-83-3, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 5g
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