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SAFE AND SURE NEDERLAND B.V.
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SAFE AND SURE NEDERLAND B.V.
Supplier:
Enzo Life Sciences
Description:
Wnt activator
Supplier:
Enzo Life Sciences
Description:
Methyltransferase inhibitor
Catalog Number:
(76002-938)
Supplier:
Enzo Life Sciences
Description:
Recommended Applications: IF, IP, WB
Species reactivity:
Catalog Number:
(89148-656)
Supplier:
Enzo Life Sciences
Supplier:
Enzo Life Sciences
Description:
PKC inhibitor
Supplier:
Enzo Life Sciences
Description:
Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.
Catalog Number:
(89164-332)
Supplier:
Enzo Life Sciences
Description:
Produced in Sf9 cells. Recombinant human MKP-2 fused at the N-terminus to a His-tag.
Catalog Number:
(89146-042)
Supplier:
Enzo Life Sciences
Description:
Host: Rabbit
Catalog Number:
(89165-156)
Supplier:
Enzo Life Sciences
Description:
Produced in E. coli BL21 (λDE3).
Catalog Number:
(89163-818)
Supplier:
Enzo Life Sciences
Description:
Produced in <i>E. coli</i>. Mouse caspase-11 (aa 81-373).
Catalog Number:
(89153-504)
Supplier:
Enzo Life Sciences
Description:
All members of the inhibitor of apoptosis proteins (IAP) family contain at least one, but usually three copies of baculovirus IAP repeat (BIR), a ~70-aa zinc binding domain, and upon overexpression suppress apoptosis. The BIR motif is capable of interacting with caspases and occluding their catalytic pockets. Certain IAPs also possess C-terminal RING domains. RING-containing proteins often act as E3 ubiquitin ligases and can catalyse the degradation of both, themselves and selected target proteins through ubiquitylation. So far, eight human IAPs have been identified: Apollon (Bruce), c-IAP1 (HIAP2; MIHB), c-IAP2 (HIAP1; MIHC), ILP-2 (Ts-IAP), Livin (ML-IAP; KIAP), NAIP, Survivin (TIAP) and XIAP (ILP-1; MIHA). c-IAP1 has been shown to inhibit specific caspases.
Catalog Number:
(89154-092)
Supplier:
Enzo Life Sciences
Description:
Host: Rat, Isotype: IgG2a
Catalog Number:
(89152-446)
Supplier:
Enzo Life Sciences
Description:
Ca2+ channel inhibitor
Supplier:
Enzo Life Sciences
Description:
Irreversible, cell permeable broad-spectrum caspase inhibitor.
Catalog Number:
(89155-944)
Supplier:
Enzo Life Sciences
Description:
ELISAFunctional Application: Stimulates the proliferation of mouse B cells and dendritic cells. The activity of CD40L increases 1'000-fold (stimulation in the ng/ml range) in the presence of the cross-linking enhancer (Prod. No. ALX-804-034).
Catalog Number:
(89150-584)
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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