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SAFE AND SURE NEDERLAND B.V.
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SAFE AND SURE NEDERLAND B.V.
Catalog Number:
(89150-362)
Supplier:
Enzo Life Sciences
Description:
Fluoroquinolone antibacterial agent
Catalog Number:
(89150-650)
Supplier:
Enzo Life Sciences
Description:
Cell permeable modulator of Ins(1,4,5)-P3-induced Ca2+ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca2+ entry (75µM).
Supplier:
Enzo Life Sciences
Description:
Tyrosine kinase inhibitor
Catalog Number:
(89148-852)
Supplier:
Enzo Life Sciences
Description:
Isoins(1,4,5)P3/PM (caged) 98 HPLC_ASSAY_METHOD
Supplier:
Enzo Life Sciences
Description:
Inhibitor of PP1 and PP2A
Catalog Number:
(89150-054)
Supplier:
Enzo Life Sciences
Description:
Topoisomerase II inhibitor
Catalog Number:
(89147-900)
Supplier:
Enzo Life Sciences
Description:
Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).
Supplier:
Enzo Life Sciences
Description:
PARP inhibitor
Supplier:
Enzo Life Sciences
Description:
Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=23nM, 4nM and 18nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). Minimally affects a panel of 9 closely related kinases including p38 MAPK (IC50>16µM).
Catalog Number:
(89147-716)
Supplier:
Enzo Life Sciences
Description:
Potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor (IC50=450nM). Neuroprotectant.
Catalog Number:
(89147-664)
Supplier:
Enzo Life Sciences
Description:
Represents a class of natural compounds, which inhibit proliferation in eukaryotes by blocking nuclear export. As potent as leptomycin B (Prod. No. ALX-380-100) and specific for G1/S checkpoint. Cytotoxic secondary metabolite (IC50=50pg/ml in mouse cell line L929) that arrests tumor cells in the G1 phase at remarkably low concentrations (50pg/ml in HeLa cell line KB3.1). Inhibits the binding between the nuclear export signal (NES) of proteins and the chromosome maintenance region protein (CRM1). Anticancer compound. Belongs to the family of orphan ligands which include polyketides like leptomycin B, callystatin A and other related compounds.
Supplier:
Enzo Life Sciences
Description:
Inhibitor of Lipoxygenase and COX
Supplier:
Enzo Life Sciences
Description:
PP2A inhibitor
Supplier:
Enzo Life Sciences
Description:
Nampt inhibitor
Catalog Number:
(89148-126)
Supplier:
Enzo Life Sciences
Description:
Cell permeable inhibitor human (IC50=4µM), fission yeast (IC50=5µM), S. cerevisiae (IC50=12µM) and bovine (IC50=17µM) Arp2/3 complex between Arp2 and Arp3. Inhibits Listeria motility (IC50=7µM).
Supplier:
Enzo Life Sciences
Description:
Potent inhibitor of histone deacetylases (HDACs) (IC50≤1µM).
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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