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BIOTIUM, INC
Supplier:
Biotium
Description:
MAGE A1, Monoclonal antibody, Clone: MA454, Host: Mouse, Species reactivity: Human, Dog, Rat, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Human MAGE-A1 full length recombinant protein, Synonyms: MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
Eosinophil Peroxidase Monoclonal antibody, Clone: EPO104, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF640R, Immunogen: Human eosinophils, hypereosinophilic syndrome, Synonyms: EPER, Application: IF, Size: 500 uL
Supplier:
Biotium
Description:
The epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Supplier:
Biotium
Description:
PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: 3H9, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF594, Immunogen: synthetic peptide from N-terminal of PTH, Synonyms: hPTH, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
Myogenin, Monoclonal antibody, Clone: F5D, Host: Mouse, Species reactivity: Pig, Dog, Cat, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Rat myogenin peptide (aa 73-94), recombinant fragment (aa30-224), Synonym:cb553, Size: 100uL
Supplier:
Biotium
Description:
was conjugated to biotin. Useful for three step labelings with conjugated streptavidins or avidins.
Catalog Number:
(89139-790)
Supplier:
Biotium
Description:
Disufide crosslinks of cystines in proteins can be reduced to cysteine residues by TCEP (tris-(2-carboxyethyl)phosphine). Unlike DTT (dithiothreitol), TCEP does not contain thiols and therefore usually does not need to be removed prior to thiol modification.
Supplier:
Biotium
Description:
Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
Cytokeratin 18 Monoclonal antibody, Clone: KRT18/836, Host: Mouse, Species reactivity: Human, Dog, Cat, Isotype: IgG1, Conjugate: CF488A, Immunogen: Recom human KRT18 protein, Synonyms: K18, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
Lambda Light Chain, Monoclonal antibody, Clone: ICO-106, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF568, Immunogen: Purified IgG myeloma proteins coupled to polyaminostyren, Synonyms: BJP, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
EGFr Monoclonal antibody, Clone: B1D8, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: biotin, Immunogen: Microsomes from A431 cells, Synonyms: Erbb1, ERBB1, Application: FC, Affinity purification, IP, Size: 500 uL
Supplier:
Biotium
Description:
GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: F1G4, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow, Size: 500uL
Supplier:
Biotium
Description:
Conjugates are particULarly usefUL for mULti-color fluorescence staining in combination with our CF350, CF488A, and CF647 conjugates.
Catalog Number:
(75975-996)
Supplier:
Biotium
Description:
In Western blotting, this antibody reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Supplier:
Biotium
Description:
This antibody recognizes a non-histone protein of 36 kDa, which is identified as proliferating cell nuclear antigen (PCNA). It is also known as cyclin or polymerase delta auxiliary protein. Elevated expression of PCNA/cyclin has been shown in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and M phases. This MAb is excellent for multiple applications.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number:
(75966-344)
Supplier:
Biotium
Description:
Nuclear Membrane, Monoclonal antibody, Clone: NM97, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, BSA-free, Immunogen: Nuclei of myeloid leukemia biopsy cells, Application: Immunofluorescence, Size: 50 uL
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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