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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

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E. Becker & Co. GmbH


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Supplier:  MP Biomedicals
Description:   Amphotericin B is a polyene antifungal antibiotic from Streptomyces. It has an affinity for sterols, primarily ergosterols, of fungal cell membranes. It forms channels in the membranes, causing small molecules to leak out which contributes to cell death.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Lysozyme (muramidase) hydrolyzes preferentially the b-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus.
Supplier:  MP Biomedicals
Description:   Dextran is a high molecular weight polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(1-->6) linkages. Dextrans with molecular weights greater than 10,000 behave as if they are highly branched. As the molecular weight increases, dextran molecules attain greater symmetry. Solutions of 10% dextran (MW ~40,000) exert a slightly higher colloidal osmotic pressure than plasma proteins.
MSDS SDS
Supplier:  MP Biomedicals
Description:   N-(1-Naphthyl)ethylenediamine, dihydrochoride is used for colorimetric determination of sulfonamide in blood. It is used for spectrophotometric determiniation of nitrite and nitrate.
MSDS SDS
Supplier:  MP Biomedicals
Description:   (+/-)-Epinephrine is also known as adrenaline and is a hormone as well as a neurotransmitter that is part of a group of monoamines called catecholamines.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Actinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Bovine albumin is a single polypeptide chain consisting of approximately 583 to 595 amino acid residues and no carbohydrates. At pH 5-7 it contains 17 intrachain disulfide bridges and 1 sulfhydryl group.
Supplier:  MP Biomedicals
Description:   N-Dodecane is a liquid alkane hydrocarbon.
N-Dodecane is used as a solvent, distillation chaser, scintillator component. Moreover it is used as a diluent for tributyl phosphate (TBP) in plants reprocessing.
Catalog Number: (IC15211905)

Supplier:  MP Biomedicals
Description:   Tetramisole is an alkaline phosphatase inhibitor. It is a racemic mixture of (+) and (-) isomers. The (-) isomer (levamisole) accounts for most of the biological activity of tetramisole.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Serum, Goat is suitable replacement for FBS on most cell lines and primary cultures for Biomedical Research - virus isolation and identification, virological studies, etc
Supplier:  MP Biomedicals
Description:   Cholesterol is the principal sterol of the higher animals, found in all body tissues. It is the main constituent of gallstones and all biological membranes. Approximately 25% of total brain lipid is cholesterol.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Sodium azide used as a preservative for laboratory reagents; a bacteriostatic agent in storage solutions. Inhibits gram negative flora so is therefore included in culture media for the selective isolation of Streptococci and Staphylococci. It has been used to avoid bacterial contamination during RPC-5 column chromatography of DNA fragments.
Catalyst for:
• Oxidative decarboxylation
• Michael addition reactions
Reagent for synthesis of
• Blue fluorescent copolymers
• Metal phosphonates
• Arenes via aminations
Involved in regioselective synthesis of prianosin B
It is also a useful probe reagent, mutagen, and preservative. In hospitals and laboratories, it is a biocide (A biocide is a chemical substance or microorganism which can deter, render harmless, or exert a controlling effect on any harmful organism by chemical or biological means.)
Sodium Azide is an inhibitor of peroxidase, myeloperoxidase, superoxide dismutase, galactose oxidase, catalase, haemoprotein enzymes and O2 evolution in photosynthesis. The mechanism of its inhibition and toxicity may be due to metal ion complexation and displacement from enzyme.
Supplier:  MP Biomedicals
Description:   Alcohol dehydrogenases are a group of dehydrogenase enzymes that occur in many organisms. It is a metalloenzyme containing four tightly bound zinc atoms per molecule. Each subunit also contains a second zinc atom (conformational zinc), which stabilizes the enzyme’s tertiary structure. Per subunit, there are two distinct active site sulfhydryl groups which can be distinguished on the basis of differential reactivity with iodoacetate and butyl isocyanate. A histidine residue is considered to have an essential role.
Supplier:  MP Biomedicals
Description:   Guanidine Hydrochloride is a protein denaturant and thus having an important role in molecular weight determinations.
Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties. It is an inhibitor of RNase. Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins. It apparently disrupts hydrogen bonds which hold the protein in its unique structure. However, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions.
Supplier:  MP Biomedicals
Description:   Background Information
Fibrinogen is a blood protein that is involved in clotting and is converted to fibrin by thrombin. Fibrinogen has an approximate molecular weight of 340 kDa. It consists of three non-identical pairs of disulfidebonded chains. The α-chain has an approximate molecular weight of 63.5 kDa, the β-chain 56 kDa, and the γ-chain 47 kDa. At the amino termini, the three chains are connected in a dimeric disulfide knot (DSK). A second DSK occurs later in the molecule. Fibrinogen has approximately 4% carbohydrate content.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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