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DIAGNOSTIC BIOSYSTEMS INC
Catalog Number:
(95027-174)
Supplier:
Diagnostic Biosystems
Description:
This kit stains acid mucins, carboxylated and sulfated mucosubstances (except strongly sulfated mucosubstances) in paraffin tissue sections
Catalog Number:
(95027-214)
Supplier:
Diagnostic Biosystems
Description:
This kit stains collagen, fibrin and striated muscle in paraffin tissue sections
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to an oncofetal antigen of >1,000 kDa known as tumor associated glycoprotein (TAG-72) or CA 72-4. This antibody defines the mucin carried sialylated-Tn antigen. This antibody stains the majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary and non-small cell lung cancer.
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes heavy chain of human skeletal myosin. It does not stain cardiac or smooth muscle myosin. This antibody stains the fast twitch (type II) isomyosin molecule.
Supplier:
Diagnostic Biosystems
Description:
CD4 is glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It is a co-receptor that assists the T-cell receptor (TCR) with antigen-presenting cell and also interacts directly with MHC class II molecules of the surface of antigen presenting cells. Most mature T-cell lymphomas are CD4 positive with the exception of aggressive NK-cell leukemia and extranodal NL/T-cell lymphoma. CD4 plays an important role in the classification of lymphocytes in inflammatory legions and malignant lymphomas.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to a 48 kDa protein, which is identified as cytokeratin 16. Cytokeratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region. High concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins.
Supplier:
Diagnostic Biosystems
Description:
p63 is a homolog of the tumor suppressor p53, it is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63, vital for the development of the prostate and selectively expressed by normal prostate basal cells, has been shown to be a promising complementary basal cell specific marker to High Molecular Weight-Cytokeratin (HMW-CK), for the differential diagnosis of benign prostatic lesions and prostatic carcinoma. p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90% . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Catalog Number:
(95024-890)
Supplier:
Diagnostic Biosystems
Description:
Clone33-2-5 .5Ml
Supplier:
Diagnostic Biosystems
Description:
The antibody is specific against human α-1-antitrypsin. This antibody stains macrophages in human tissues and does not stain any other cell type.
Catalog Number:
(76634-506)
Supplier:
Diagnostic Biosystems
Description:
This antibody stains with ORF-73 of human herpesvirus 8 (HHV8). HHV8 is the likely etiological agent of Kaposi sarcoma (KS). HHV8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene ORF 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity.
Supplier:
Diagnostic Biosystems
Description:
CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Supplier:
Diagnostic Biosystems
Description:
Cytokeratin 5 (58 kDa) is a high molecular weight, basic type of cytokeratin expressed in basal, intermediate and superficial cell layers of stratified epithelia as well as transitional epithelia, complex epithelia and in mesothelial cells and mesothelioma. Cytokeratin 6 (56 kDa) is also a high molecular weight, basic type cytokeratin expressed by proliferating squamous epithelium often paired with cytokeratin 16.
Catalog Number:
(99990-898)
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the heavy chain present in all types of human IgM. It stains B cell follicles in human lymphoid tissues. In lymphoid tissues, IgM containing plasma cells stain strongly but immune complexes are usually undetectable.
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes a protein of 25-26kDa, identified as bcl-2 alpha oncoprotein. It shows no cross-reaction with BCL-X or BAX protein. Expression of BCL-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. This antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express BCL-2 protein and small number in which neoplastic cells are BCL-2 negative.
Catalog Number:
(76634-542)
Supplier:
Diagnostic Biosystems
Description:
SOX10 is widely expressed in normal human tissues including melanocytes and breast tissue. SOX10 is also an important marker in malignant tumors such as melanoma, breast carcinoma, gliomas, and benign tumors such as schwannomas.SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Supplier:
Diagnostic Biosystems
Description:
Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. Uroplakins are markers of terminally differentiated urothelium. Uroplakin II (UPII) is a newly described sensitive marker for urothelial carcinoma (UC). The expression profile of UPII in different types of UC and its utility in the diagnostic setting are needed.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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