DIAGNOSTIC BIOSYSTEMS INC
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes CD23. CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukemia and some cases of centroblastic/centrocytic lymphoma.
Catalog Number:
(95027-222)
Supplier:
Diagnostic Biosystems
Description:
The Copper Stain Kit (For Microwave) is intended for the demonstration of copper deposits in tissue sections.
Catalog Number:
(95025-198)
Supplier:
Diagnostic Biosystems
Description:
Peroxidase Mouse and Rabbit Kit (DAB Liquid)
Catalog Number:
(95027-190)
Supplier:
Diagnostic Biosystems
Description:
This kit stains fungi and Pneumocystis carinii in paraffin tissue sections
Catalog Number:
(76634-296)
Supplier:
Diagnostic Biosystems
Description:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pH <5.7) and basic (pH >6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad-spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g., squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes purified insulin from the pancreas of human, as well as proinsulin from human.
Catalog Number:
(76634-840)
Supplier:
Diagnostic Biosystems
Description:
The progesterone receptor (PgR) is an estrogen-regulated protein. It has been proposed that expression of PgR indicates a responsive estrogen receptor (ER) pathway. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies.
Catalog Number:
(76634-454)
Supplier:
Diagnostic Biosystems
Description:
Inhibin is a dimeric glycoprotein hormone from the TGF-β family made of α and β subunits. This antibody recognizes the 32kDa α subunit of human inhibin. Inhibin α is expressed in a wide variety of human tissues, such as brain, prostate, adrenal, granulose cells of ovary, sertoli cells of testis and in fetoplacental unit.
Supplier:
Diagnostic Biosystems
Description:
Rabbit .5Ml
Supplier:
Diagnostic Biosystems
Description:
This antibody labels melanocytes and is a useful tool for the identification of melanomas and clear cell sarcomas. Anti-Melanoma, PNL2, seems to be a melanocyte antibody of autoimmune origin as it does not react with the non-melanocytic peptide antigen used for immunization.
Catalog Number:
(99990-094)
Supplier:
Diagnostic Biosystems
Description:
Endogenous peroxidase activity has been observed in tissue sections during immunoperoxidase staining. If not properly suppressed, endogenous peroxidase can produce false signal as well as high background during the immunostaining. Treatment of tissue sections with Peroxidase Block prior to the application of primary antibody will suppress endogenous peroxidase activity.
Supplier:
Diagnostic Biosystems
Description:
Clone number XM26&LL002, This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50 kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kD protein, which is closely related to cytokeratin 6. .
Supplier:
Diagnostic Biosystems
Description:
UnoVue Mouse/Rabbit AP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and cryostat sections.
Catalog Number:
(76634-534)
Supplier:
Diagnostic Biosystems
Description:
Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin s disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the 57 kDa intermediate filament protein present in the cells of mesenchymal origin. The antibody does not show any cross-reactivity with other intermediate filament proteins.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to constitutive (HSP73) and inducible (HSP72) form of HSP70. HSP70 is found to be associated with steroid receptors, actin, P53, polyoma T antigen, nucleotides and other known proteins. HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs and other damaging conditions.
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