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Van Der Voort Lucht en Milieu Amste
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Van Der Voort Lucht en Milieu Amste
Catalog Number:
(102980-422)
Supplier:
Adipogen
Description:
NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions
Catalog Number:
(102512-400)
Supplier:
Adipogen
Description:
Human CD49d molecules are integrin alpha4 chains that are expressed as heterodimers with CD29 (beta 1 integrin) or (beta 7 integrin) and function as adhesion receptors. CD49d/CD29 is mainly expressed on thymocytes and B cells with increased expression on activated T cells. The ligands for CD49d/CD29 include VCAM-1 and fibronectin.
Catalog Number:
(102988-408)
Supplier:
Adipogen
Description:
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM3 is the most abundant ganglioside in mammals. It is involved in several tumor processes by interacting with receptors. It inhibits epidermal cell growth and blocks insulin receptor activity.
Supplier:
Adipogen
Description:
Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html. Mycotoxin. So far no comparison to aphidicolin's biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.
Catalog Number:
(102512-262)
Supplier:
Adipogen
Description:
Human CD35 binds complement components C3b, C4b and iC3b and is expressed on erythrocytes, B cells, monocytes, granulocytes and folicular dendritic cells and on subsets of thymocytes. CD35 on erythrocytes mediates clearance of immune complexes.
Supplier:
Adipogen
Description:
Reference standard.
Supplier:
Adipogen
Description:
Used in the Seyferth-Gilbert homologation which is a chemical reaction of an aryl ketone or aldehyde with dimethyl- or diazomethyl-phosphonate and potassium tert-butoxide to give substituted alkynes.
Supplier:
Adipogen
Description:
Glutathione peroxidase mimetic. Peroxynitrite scavenger. Anti-inflammatory Antioxidant. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor. Antifungal. Review. Potent IDO-1 inhibitor with Ki 94nM. Inhibitor of HIV-1 capsid C-terminal domain dimerization.
Catalog Number:
(102513-358)
Supplier:
Adipogen
Description:
Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis.
Catalog Number:
(102512-804)
Supplier:
Adipogen
Description:
Immunoglobulin expressed by the mouse plasmacytoma hybridoma RPC 5 is an IgG2a isotype of unknown specificity. It is used as a negative control when working with human cells.
Catalog Number:
(102514-468)
Supplier:
Adipogen
Description:
FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
Catalog Number:
(102512-978)
Supplier:
Adipogen
Description:
Human CD106 is an endothelial adhesion molecule that binds to alpha 4 beta 1 and alpha 4 beta 7 integrins (VLA-4) and promotes adhesion of lymphocytes, monocytes, eosinophils and basophils. CD106 is also found on follicular dendritic cells, interdigitating recticulum cells and Kupffer cells.
Catalog Number:
(102512-064)
Supplier:
Adipogen
Description:
Human CD16 is a low affinity receptor for complexed IgG and occurs in two distinct forms, as a glycosyl phosphatidyl inositol (GPI) anchored protein in granulocytes and as an integral membrane protein on NK cells and macrophages.
Catalog Number:
(102512-102)
Supplier:
Adipogen
Description:
Human CD19 is a B cell restricted membrane protein expressed from early stages of B cell development and associates with the antigen receptor complex. CD19 is involved in the regulation of B cell proliferation.
Catalog Number:
(102511-322)
Supplier:
Adipogen
Description:
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
Supplier:
Adipogen
Description:
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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