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Van Der Voort Lucht en Milieu Amste
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Van Der Voort Lucht en Milieu Amste
Supplier:
Adipogen
Description:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Catalog Number:
(102512-256)
Supplier:
Adipogen
Description:
Human CD34 is an unusual glycosylated membrane protein exclusively expressed on immature hematopoietic cells and on endothelial cells. CD34 may have a role in cell adhesion. CD34 has extensive utility for bone marrow transplantation.
Supplier:
Adipogen
Description:
IPI-145 is a potent, oral inhibitor of Class I phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma (IC(50) of 243 pM and 50nM), and is clinically active in patients with advanced hematological malignancies.
Supplier:
Adipogen
Description:
N-Heptanoyl-L-homoserine lactone (C7-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The diverse applications of this molecule include regulation of virulence, infection prevention and septicemia in fish.
Catalog Number:
(102511-952)
Supplier:
Adipogen
Description:
Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33kDa. CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells. CD8 is a co-receptor involved in antigen recognition and binds to the alpha2 and alpha3 domain of MHC Class I molecules.
Catalog Number:
(102979-972)
Supplier:
Adipogen
Description:
Lipoma preferred partner (LPP) is encoded by the preferred fusion partner gene of the high mobility group protein HMGI-C. LPP is frequently affected by chromosomal translocations in a major group of soft tissue lipomas, as well as in a parosteal lipoma and in pulmonary chondroid hamartomas. The resulting fusion proteins comprise three DNA binding domains of HMGI-C fused to two or three C-terminal LIM domains of LPP and a reciprocal product, respectively. Expression of a HMGI-C/LPP fusion protein causes malignant transformation of fibroblasts. Similar to its relatives zyxin and TRIP (thyroid receptor interacting protein 6) / ZRP-1 (zyxin-related protein 1), LPP consists of a N-terminal proline-rich domain followed by three C-terminal LIM domains (double zinc finger structures that are involved in protein-protein interactions). Like the cytoskeletal protein zyxin, LPP localizes to focal adhesions and cell-cell adherens junctions. LPP harbors a nuclear export signal and displays transcriptional activation capacity.
Supplier:
Adipogen
Description:
Intercalating probe for nucleic acids. Other applications include the determination of cationic surfactants.
Catalog Number:
(102991-930)
Supplier:
Adipogen
Description:
SU-6668 is a potent ATP-competitive PDGFR, VEGF and FGFR inhibitor. It has a Ki of 8nM against PDGFR. It is an anti-angiogenic and anti-tumor agent that induces regression of established tumors.
Supplier:
Adipogen
Description:
TAK-715 is a potent specific inhibitor of the p38alpha MAP kinase with an IC(50) of 7.1nM. It is approximately 30-fold more selective for p38alpha over p38beta. It shows no inhibition of p38gamma/delta.
Catalog Number:
(102988-746)
Supplier:
Adipogen
Description:
Synthetic, soluble analog of alpha-galactosylceramide . Immunostimulant. Potent stimulator of natural killer T (NKT) cells. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells.
Supplier:
Adipogen
Description:
Colorimetric reagent for Mg detection. The aqueous solution of XB-1 is red, and turns reddish-violet in the presence of Mg at pH 9 (maximum wavelength: 510 nm, molar absorptivity: 49,000, detection range 0.02-0.4 ppm).
Supplier:
Adipogen
Description:
Building block for synthesis.
Supplier:
Adipogen
Description:
Reagent for the spectrophotometric det. of Ag and Ru. Tridentate ligand that binds metals at three meridional sites giving two adjacent 5-membered MN2C2 chelate rings. It forms complexes with most transition metal ions. It is also a potent inducer of nitrate and nitric oxide (NO) synthase (iNOS) protein and mRNA production in the cultured murine macrophage RAW 264.7 cell line.
Supplier:
Adipogen
Description:
Motesanib (AMG 706) is a multi-targeted anti-cancer agent with an inhibitory action on human vascular endothelial growth factor receptors 1, 2 and 3 (VEGFR1-3) with IC(50) values of 2nM, 3nM and 6nM. It also inhibits platelet-derived growth factor receptor (PDGFR) and cellular stem-cell factor receptor (c-KIT).
Supplier:
Adipogen
Description:
Substrate for Cytochrome P-450. Used for various investigations including the differentiatiation of cytochrome P-450 isozymes.
Supplier:
Adipogen
Description:
N-(3-Oxotetradecanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter acyl chain AHLs in developing biofilms and like other long chain 3-oxo-AHLs, stimulates the production of putisolvin, which in turn inhibits biofilm formation.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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