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5-(sec-Butyl)-2-methoxybenzaldehyde
Supplier:
AMBEED, INC
Description:
(3-Fluoro-5-iodophenyl)methanol, Purity: 97%, CAS Number: 1261837-87-9, Appearance: Liquid or Solid or Semi-solid or lump, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 1g
Supplier:
AMBEED, INC
Description:
N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide dimethyl sulfoxide complex 98%
Catalog Number:
(77266-050)
Supplier:
AMBEED, INC
Description:
(2-Iodophenyl)(methyl)sulfane, Purity: 95%, CAS Number: 33775-94-9, Appearance: Liquid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 250mg
Catalog Number:
(10304-176)
Supplier:
Bioss
Description:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
Supplier:
AMBEED, INC
Description:
4-Bromo-2-iodoanisole 98%
Supplier:
AMBEED, INC
Description:
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione, Purity: 98%, CAS Number: 871700-24-2, Appearance: White to Yellow Powder or crystals, Storage: Keep in dark place, Sealed in dry, 2-8 deg C, Size: 100mg
Supplier:
AMBEED, INC
Description:
ω-Bromo-4-iodoacetophenone 95%
Catalog Number:
(89157-116)
Supplier:
Enzo Life Sciences
Description:
Cannabinoid receptor ligand.
Catalog Number:
(10304-182)
Supplier:
Bioss
Description:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2'-Iodoacetophenone 99+%
Supplier:
AMBEED, INC
Description:
4-Iodobenzophenone 95%
Supplier:
AMBEED, INC
Description:
5-Chloro-2-iodoanisole 95%
Catalog Number:
(77170-260)
Supplier:
AMBEED, INC
Description:
(2-Fluoro-6-iodophenyl)methanol, Purity: 98+%, CAS Number: 911825-94-0, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 1g
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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