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Dithiothreitol (DTT, Cleland's reagent)
Supplier:
VWR
Description:
An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Typically, a seven fold lower concentration of DTT (100 mM) is needed than is used for 2-mercaptoethanol (5% v/v, 700 mM).
Catalog Number:
(JTF781-5)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
White crystals. Keep material refrigerated between 2 to 8°C.
Catalog Number:
(IC856126)
Supplier:
MP Biomedicals
Description:
DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes. Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Useful for stabilizing sulfhydryl-containing enzymes.
Supplier:
Enzo Life Sciences
Description:
Protective agent for SH groups
Supplier:
MP Biomedicals
Description:
DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
DTT has been used:
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Dithiothreitol (DTT, Cleland's reagent) 99% for biochemistry
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Dithiothreitol (DTT, Cleland's reagent) 99+% for molecular biology DNase-, RNase-, protease-free
Supplier:
MP Biomedicals
Description:
DL-Dithiothreitol is a Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Dithiothreitol (DTT, Cleland's reagent) 98%, pure
Supplier:
RPI
Description:
Protective reagent for maintaining -SH groups in reduced state.
Supplier:
Thermo Scientific Chemicals
Description:
Useful for stabilizing sulfhydryl-containing enzymes
Supplier:
TCI America
Description:
CAS Number: 3483-12-3
MDL Number: MFCD00004877 Molecular Formula: C4H10O2S2 Molecular Weight: 154.24 Purity/Analysis Method: >98.0% (T) Form: Crystal Boiling point (°C): 130 Melting point (°C): 43 Flash Point (°C): 113 Storage Temperature: 0-10°C
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Dithiothreitol (DTT, Cleland's reagent) 1 M in water for biochemistry
Supplier:
TCI America
Description:
CAS Number: 3483-12-3
MDL Number: MFCD00004877 Molecular Formula: C4H10O2S2 Molecular Weight: 154.24 Purity/Analysis Method: >98.0% (T) Form: Crystal Boiling point (°C): 130 Melting point (°C): 43 Flash Point (°C): 113 Storage Temperature: 0-10°C
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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