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(1H-Pyrazol-4-yl)methanol
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(1H-Pyrazol-4-yl)methanol
Catalog Number:
(76870-628)
Supplier:
AMBEED, INC
Description:
1-tert-Butylpyrazole-4-boronic acid, pinacol ester 97%
Supplier:
Adipogen
Description:
PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Supplier:
Adipogen
Description:
Baricitinib is a selective JAK1 and JAK2 inhibitor. IC(50) values are 5.9nm for JAK1, and 5.7nM for JAK2. In cell based assays Baricitinib/INCB-28050 demonstrated inhibition of intracellular signaling of multiple pro-inflammatory cytokines including IL-6 and IL-23 at concentrations of <lt/> 50nM, and also showed good efficacy in a number of animal models at doses of 10mg/kg and below. Baricitinib is in Phase III development as a potential treatment for rheumatoid arthritis. It is in Phase II development as a potential treatment for psoriasis and diabetic nephropathy
Supplier:
Adipogen
Description:
INCB018424 is a JAK inhibitor with an IC(50) values of 2.7nM and 4.5nM, respectively for JAK1 and JAK2.
Supplier:
ALADDIN SCIENTIFIC
Description:
Product Describtion:AMG-458 is a potent, selective and orally bioavailable c-Met inhibitor, with Ki values of 1.2 nM and 2.0 nM for human and mouse c-Met, respectively.
Supplier:
AMBEED, INC
Description:
4'-(1-Pyrazolyl)acetophenone, Purity: 97%, CAS Number: 25699-98-3, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8 C, Size: 10g
Catalog Number:
(101793-658)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 007919-500MG , MDL Number: MFCD00996156
Supplier:
Adipogen
Description:
SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC(50) of 4nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7nM) than the more active phospho-enzyme (Ki = 23nM). In a broad panel of 213 kinases, SGX523 was extremely selective, with no inhibition >36%, suggesting IC(50) values > 1µM, including the closely-associated RON kinase.
Supplier:
Adipogen
Description:
AMG-1 is a potent inhibitor of human c-Met and RON with IC(50) values of 4 and 9nM respectively.
Catalog Number:
(77280-740)
Supplier:
AMBEED, INC
Description:
3-(1-Pyrazolyl)propionic Acid, Purity: 98%, CAS Number: 89532-73-0, Appearance: Off white to yellow solid, Storage: Sealed in dry, 2-8 C, Size: 250mg
Supplier:
Adipogen
Description:
Antibiotic
Supplier:
Adipogen
Description:
AG13958 is a VEGF inhibitor that was in clinical development for treatment of age-related macular degeneration (AMD). The drug displays low water solubility and so far in trials delivery has been difficult needing direct injection to be truly effective and it varied by the species used because of species specific differences in eye circulation and vascularization. As a VEGF inhibitor AG13958 was targeted to FLT/TYK receptor inhibition.
Supplier:
Adipogen
Description:
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Supplier:
Adipogen
Description:
AMG-458 is a potent inhibitor of c-Met with an IC(50) of 60nM and displays selectivity against VEGFR2.
Supplier:
Adipogen
Description:
XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM)
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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