(2,3-difluorophenyl)(4-methylpiperazin-1-yl)methanone
Catalog Number:
(80056-706)
Supplier:
MilliporeSigma
Description:
Cell-permeable, adenine-thymine-specific fluorescent stain
Supplier:
Adipogen
Description:
Intedanib is an indolinone derivative that potently inhibits VEGFR1/2/3, FGFR1/2/3 and PDGFRalpha/beta with IC(50) values of 34, 13, 13, 69, 37, 108, 59 and 65nM.
Supplier:
TCI America
Description:
CAS Number: 1249-97-4
MDL Number: MFCD00059153 Molecular Formula: C23H23N3OS Molecular Weight: 389.52 Purity/Analysis Method: >96.0% (HPLC,T) Form: Crystal Melting point (°C): 198
Supplier:
AMBEED, INC
Description:
N-((S)-1-Amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide, Purity: 99+%, CAS Number: 1047644-62-1, Appearance: White to off-white powder, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 1g
Catalog Number:
(PI62249)
Supplier:
Invitrogen
Description:
Hoechst 33342 fluorescent stain is a high-quality solution of Hoechst dye for fixed- and live-cell fluorescent staining of DNA and nuclei in cellular imaging techniques.
Supplier:
MilliporeSigma
Description:
Membrane-permeable, adenine-thymine-specific fluorescent stain
Catalog Number:
(ALA151515-5G)
Supplier:
ALADDIN SCIENTIFIC
Description:
3-Amino-5-phenylpyrazole ((3-phenyl-1H-pyrazol-5-amine) may be used in the synthesis of the following: · Urea derivatives by reaction with azido(6-(benzofuran-2-yl)-2-methylpyridin-3-yl) methanone. · 2-Mercaptoacetamide analogs by treating with thioglycolic acid. · 3-(Substituentpyrimidayl)-5,6-benzocoumarins by treating with 3-(2′-formyl-1′-chlorovinyl)-5,6-benzocoumarin. · Substituted 2,7-diphenylpyrazolo[1,5-a]pyrimidine-5-carboxylic esters by reacting with substituted β-diketo esters. · N-ethoxycarbonylthiourea derivative by reacting with ethoxycarbonyl isothiocyanate. · Heterobiaryl pyrazolo[3,4-b]pyridines by reacting with indole-3-carboxaldehyde.
Catalog Number:
(89158-838)
Supplier:
Enzo Life Sciences
Description:
A selective estrogen receptor modulator (SERM). Displays anti-estrogen action along with anti-androgen action. In clinical use for prevention of postmenopausal osteoporosis. Reduces circulating levels of IL-6 and TNFα. Inhibits prostate carcinogenesis in transgenic rat model. May be useful for the prevention of hormone-related cancers.
Supplier:
AMBEED, INC
Description:
2-(3,5-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, Purity: 98%, CAS Number: 863868-36-4, Appearance: White to Light yellow powder to crystal, Storage: Sealed in dry, Room Temperature, Size: 5G
Supplier:
BeanTown Chemical
Description:
CAS: 530-62-1; EC No: 208-488-9; MDL No: MFCD00005286
UN No: UN3263; Haz Class: 8; Packing Group: II
Solid; Molecular Formula: C7H6N4O; MW: 162.15
Melting Point: 117-122°
Moisture Sensitive
Supplier:
Adipogen
Description:
Ponatinib is a potent multi-target inhibitor of Abl, PDGFRalpha, VEGFR2, FGFR1 and Src with IC(50) values of 0.37, 1.1, 1.5, 2.2 and 5.4nM respectively.
Supplier:
Adipogen
Description:
Aurora kinases are key regulators of protein phosphorylation during mitosis, and these serine/threonine kinases interact with other cellular proteins to help control chromosome assembly and segregation during mitosis. Aurora kinases are often highly expressed in malignancies and solid tumors. Danusertib (PHA-739358) is a small molecule pan- Aurora kinase inhibitor that also has activity against other cancer-relevant kinases such as Bcr-Abl tyrosine kinase. Other off target effects of danusertib include inhibition of receptor tyrosine kinases such as FGFR-1, and TrkA. Danusertib demonstrates nanomolar IC(50) values for the Aurora kinases all under 100nM and it also demonstrates potent anti-proliferation effects in cell proliferation assays with IC(50) values ranging from 20nM for A2780 cells to <lt/>200nM.
Catalog Number:
(77613-090)
Supplier:
AMBEED, INC
Description:
PH-797804 ≥98%
Supplier:
AMBEED, INC
Description:
Altiratinib ≥98%
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