(2-Amino-5-chlorophenyl)(2,6-difluorophenyl)methanone
Supplier:
AOB CHEM USA
Description:
4-(2,3-Difluorophenyl)tetrahydro-2H-pyran-4-ol ≥97%
Supplier:
AOB CHEM USA
Description:
2-(4-Bromo-2,3-difluorophenyl)propan-2-ol ≥95%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052498-500MG , MDL Number: MFCD09863335
Supplier:
AMBEED, INC
Description:
4-Butoxy-N-(2,4-difluorophenyl)benzamide, Purity: 98+%, CAS Number: 433967-28-3, Appearance: Form: solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 50mg
Supplier:
AMBEED, INC
Description:
(S)-1-(2,5-Difluorophenyl)propan-1-amine hydrochloride, Purity: 95%, CAS number: 1391431-90-5, Appearance: White Solid, Storage: Sealed in dry, Room Temperature, Size: 1G
Supplier:
AMBEED, INC
Description:
(5-Bromopyridin-2-yl)(piperidin-1-yl)methanone, Purity: 98%, CAS Number: 934000-33-6, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1G
Supplier:
AOB CHEM USA
Description:
1-(2,3-Difluorophenyl)-2,2-difluoroethanone ≥97%
Catalog Number:
(77436-962)
Supplier:
Bioss
Description:
Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 26 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.
Catalog Number:
(76120-488)
Supplier:
Bioss
Description:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD26 (ankyrin repeat domain-containing protein 26) is a 1709 amino acid protein that contains five ANK repeats. Expressed at high level in many tissues, including brain, liver, kidney and heart, ANKRD26 may be phosphorylated upon DNA damage by Atm or ATR. ANKRD26 is also expressed in the arcuate and ventromedial nuclei within the hypothalamus and in the ependyma and the circumventricular organs that act as an interface between the peripheral circulation and the brain. It is suggested that alterations in the gene encoding ANKRD26 may lead to obesity. Three isoforms of ANKRD26 exists due to alternative splicing events.
Supplier:
AOB CHEM USA
Description:
Benzyl 2,4-difluorophenyl ether ≥97%
Catalog Number:
(AAA16584-06)
Catalog Number:
(75791-604)
Supplier:
Prosci
Description:
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and IL-1 alpha, respectively. Il1rn can Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling, but has no interleukin-1 like activity. Recently, an recombinant human Il1rn protein is used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role.
Supplier:
AOB CHEM USA
Description:
(2-Chloro-3,6-difluorophenyl)cyclopropylmethanone ≥95%
Supplier:
AMBEED, INC
Description:
(4-(Difluoromethoxy)-3,5-difluorophenyl)boronic acid, Purity: 98%, CAS Number: 915401-97-7, Appearance: Solid, Storage: Inert atmosphere, Store in freezer, under -20 deg C, Size: 5g
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