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(2-Amino-5-chlorophenyl)(2,6-difluorophenyl)methanone
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(2-Amino-5-chlorophenyl)(2,6-difluorophenyl)methanone
Supplier:
AOB CHEM USA
Description:
2,6-Dichloro-3-fluorophenol ≥97%
Catalog Number:
(102834-284)
Supplier:
Matrix Scientific
Description:
N-(4-Bromo-2,6-dimethylphenyl)-N,N-dimethylamine 97
Supplier:
AOB CHEM USA
Description:
Methyl 2,6-difluoro-4-methoxybenzoate ≥97%
Supplier:
AOB CHEM USA
Description:
2,6-Dimethyl-4-isopropoxyphenylboronic acid ≥97%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,6-Dimethoxyphenol 99%
Supplier:
AOB CHEM USA
Description:
4-Chloro-2,6-difluorobenzaldehyde ≥97%
Supplier:
AOB CHEM USA
Description:
2,6-Difluoro-3-iodobenzaldehyde ≥97%
Supplier:
AOB CHEM USA
Description:
2,6-Dichloro-4-hydroxypyridine ≥97%
Supplier:
APOLLO SCIENTIFIC
Description:
2,6-Difluoro-4-hydrazinopyridine 97%
Supplier:
AMBEED, INC
Description:
2,6-Dibromo-3-fluoropyridine 95%
Supplier:
AMBEED, INC
Description:
4-Iodo-2,6-xylenol 97%
Supplier:
AMBEED, INC
Description:
2,6-Difluorobenzenesulfonyl chloride 98%
Supplier:
AMBEED, INC
Description:
2,6-Dichloro-7-methylpurine 97%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,6-Pyridinedicarbonyl dichloride 97%
Supplier:
Adipogen
Description:
(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. In binding assays, (+)-JQ1 binds competitive with acetyl lysine to BRD4 bromodomain 1 (Kd=50nM) and and BRD4 bromodomain 2 (Kd=90 nM). May be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. (+)-JQ1 exhibited strong dose- and time-dependent inhibition of BRDT, a bromodomain-containing protein highly enriched in testis. BRDT is involved in chromatin remodeling and is essential for healthy sperm development. (+)-JQ1 appears to block that function and causes a decrease in sperm viability, being examined as a potential male contraceptive. Inhibitor of inflammation and bone destruction.
Supplier:
AOB CHEM USA
Description:
3-Bromo-2,6-dimethylaniline ≥97%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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