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Cyclopropyl(2,3-dichloropyridin-4-yl)methanone
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Cyclopropyl(2,3-dichloropyridin-4-yl)methanone
Supplier:
AMBEED, INC
Description:
Nazartinib ≥98%
Supplier:
AMBEED, INC
Description:
7-Chloroisatin 96%
Supplier:
Enzo Life Sciences
Description:
p300 HAT activator.
Catalog Number:
(490005-952)
Supplier:
MERIDIAN LIFE SCICNE, INC BE
Description:
X-Gal is a chromogenic substrate which forms an intense blue precipitate that is used to detect the presence of the gal gene and beta-galactosidase enzyme activity.
Supplier:
Enzo Life Sciences
Description:
Venetoclax is a Bcl-2-selective inhibitor with Ki of <0.01 nM, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1
Catalog Number:
(76020-284)
Supplier:
MP Biomedicals
Description:
X-Gal, is a Beta-galactosidase substrate, Ultra pure, Purity: >99%, CAS Number: 7240-90-6, Molecular Formula: C14H15BrClNO6, Molecular Weight: 408.6, Synonyms: 5-Bromo-4-chloro-3-indolyl B-D-galactoside, BCIG, Color: White, Form: Powder, Size: 1.0 g
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024709-5G , MDL Number: MFCD06657153
Catalog Number:
(TCC1646-005G)
Supplier:
TCI America
Description:
CAS Number: 4897-25-0
MDL Number: MFCD00233664 Molecular Formula: C4H4ClN3O2 Molecular Weight: 161.55 Purity/Analysis Method: >98.0% (N) Form: Crystal Melting point (°C): 147
Supplier:
Adipogen
Description:
PLX4720 is a potent and selective inhibitor of B-Raf V600E with an IC(50) of 13nM. It is equally potent to c-Raf-1 (Y340D and Y341D mutations), and shows 10-fold selectivity for B-Raf V600E over wild-type B-Raf.
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Supplier:
Thermo Scientific Chemicals
Description:
5g CAS: 7477-63-6, MDL: MFCD00022796
Catalog Number:
(77984-510)
Supplier:
LGC STANDARDS
Description:
Etoricoxib-d6, TRC, LGC Standards
Catalog Number:
(BT125150-1G)
Supplier:
BeanTown Chemical
Description:
CAS: 86-47-5; EC No: 201-673-5; MDL No: MFCD00038080; RTECS: VB1950000
Solid; Molecular Formula: C10H6ClNO3; MW: 223.61
Melting Point: 250° (decomposes)
Supplier:
MP Biomedicals
Description:
Chloroquine Diphosphate salt is member of quinolone family, Chloroquine is a lysosomotropic agent (accumulate inside the acidic parts of the cell), this accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).
Supplier:
MP Biomedicals
Description:
5-Bromo-4-chloro-3-indolyl b-D-galactopyranoside, commonly known as X-Gal, is a histochemical substrate for b-galactosidase. X-Gal is cleaved by b-galactosidase to yield an insoluble blue precipitate.
Supplier:
TCI America
Description:
CAS Number: 17422-32-1
MDL Number: MFCD00005672 Molecular Formula: C8H6ClN Molecular Weight: 151.59 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 130 Melting point (°C): 72
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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