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[3-(4-Chlorophenyl)-5-isoxazolyl]methanol


9,933  results were found

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Supplier:  Thermo Scientific Chemicals
Description:   Preparation of cadmium sulfide, as analytical lab reagent, photography, manufacturing of special mirrors, ice-nucleating agent, lubricant, to absorb H2S in sulfide analysis
MSDS SDS
Supplier:  MP Biomedicals
Description:   Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination.
Supplier:  Adipogen
Description:   Verapamil hydrochloride is an alpha-adrenergic receptor (alpha-AR) antagonist and calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein). Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models. Verapamil helps treat diabetes by limiting TXNIP expression.
Supplier:  Adipogen
Description:   Antibiotic. Antifungal. Antiprotozoal. Potent and reversible, cell permeable inhibitor of histone deacetylase (HDAC). Immunosuppressive. Anticancer compound. Antifibrogenic. Apoptosis inducer. Induces cell growth arrest at both G1 and G2/M phases. Enhances the efficacy of anticancer agents that target DNA. Inactivates mitotic spindle checkpoint. Smooth muscle cell proliferation inhibitor. Telomerase inhibitor. Downregulates DNA methyltransferase DNMT1 and affects DNA methylation. Anti-inflammatory. Inhibits osteoclastogenesis and bone resorption. Promotes either self-renewal or differentiation of embryonic stem cells.
Supplier:  MP Biomedicals
Description:   Hydrocortisone, a primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency. Hydrocortisone, known more formally as cortisone (INN, USAN, BAN), is a steroid hormone, produced by the zona fasciculata of the adrenal gland. It is released in response to stress and a low level of blood glucocorticoids.
MSDS SDS
Supplier:  Adipogen
Description:   Close structural analog of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib, that lacks COX-2 inhibitory function. Anti-proliferative, anti-tumorigenic and anti-angiogenic. Potent apoptosis inducer in many cancer cell lines. Down-regulates the expression of survivin, cyclins, MMPs and inhibits cyclin-dependent kinase activity. Modulates PDK-1, AKT, GSK3beta, p70 S6K, PKA and MAPKAP-K1alpha. Reduces phosphorylation of ERK1/2 but not AKT T-308 or AKT S-473. Increases intracellular free calcium levels and potently triggers the endoplasmatic reticulum stress response (ESR), activating ER stress-associated proteins GRP78/BiP, CHOP/GADD153 and caspase-4.
Supplier:  MP Biomedicals
Description:   Urea is a mild agent usually used in the solubilization and denaturation of proteins.
MSDS SDS
Catalog Number: (IC19144980)

Supplier:  MP Biomedicals
Description:   Succinic acid is a dicarboxylic acid that occurs in nature in such organisms as fungi and lichens. In eukaryotes, succiniate, the anion of succinic acid, is an intermediate in the citric acid cycle, being formed from succinyl CoA and being converted to fumarate. Bacteria and plants can produce succinate from acetate or acetyl CoA, in the glyoxylate cycle.
MSDS SDS
Supplier:  Adipogen
Description:   Non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively. Naproxen is a potent, non-steroidal, non-selective anti-inflammatory compound that acts as a Cox (cyclooxygenase) inhibitor, and inhibits both Cox-1 and Cox-2. Research indicates that the S-naproxen is a more active form than the R-naproxen. The S-naproxen enantiomer was observed to inhibit platelet aggregation, and both enantiomers decrease production of thromboxane B2. Naproxen has been demonstrated to block Abeta fibril growth and form a complex with copper (II).
Supplier:  Adipogen
Description:   Flow cytometry measurement tool. Fluorescence probe for glutathione and glutathione disulfide levels, primary amines, peptides and biological thiols. Reacts with primary amines to produce a product that emits a highly fluorescent blue colour. Spectral data: lambdaex 334 nm; lambdaem 455 nm (Thiol Adduct). Used for the quick visualization of histamine, characterized by the appearance of a yellow stain. Used for precolumn derivatization of amino acids for HPLC separation. High-level disinfectant/sterilant for endoscopes, thermometers, rubber and plastic equipment, and medical/surgical instruments that cannot be sterilized by heat, based on its antimicrobial efficacy and low inhalation toxicity.
Catalog Number: (IC15051625)

Supplier:  MP Biomedicals
Description:   Brilliant Green is one of the triarylmethane dyes. It is closely related to malachite green.
MSDS SDS
Supplier:  MP Biomedicals
Description:   Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts.
MSDS SDS
Supplier:  SPEX CERTIPREP LLC
Description:   Petroleum and LUST Standards

The EPA regulates the monitoring and testing of underground storage tanks (USTs), that were or are used to store petroleum or other hazardous substances, which could impact the environment and human health. Currently, there are over half a million registered underground storage tanks in the US alone. Many tanks installed prior to the mid-80s were composed of steel, which can corrode over time allowing for leakage into the surrounding groundwater and soil.

The Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act (RCRA), passed in 1984, required the US Environmental Protection Agency (EPA) to develop regulations for the underground storage of motor fuels. The EPA requires owners and operators of USTs to maintain and clean up sites damaged by petroleum contamination.

SPEX CertiPrep provides standards designed to meet the testing requirements set up by the EPA and many individual state regulations for LUST and LUFT.
Supplier:  MP Biomedicals
Description:   Sucrose is a non-reducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet, and other plants and used extensively as a food and a sweetener. The mixture of glucose and fructose is known as "invert sugar."
MSDS SDS
Supplier:  MP Biomedicals
Description:   Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. By heating the solid form to approximately 30 °C, the product can be melted without harming it's stability.
Supplier:  Adipogen
Description:   Antibiotic. Shows antiviral, antifungal and antitumor properties. Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis. Potent reversible inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), leading to depletion of GMP and interruption of the de novo synthesis of purine nucleotides necessary for B and T lymphocyte proliferation. Inhibits the type II IMPDH isoform (IMPDH-2) 5-fold more potently compared to type I isoform. Inhibits RNA and DNA synthesis. Inducible nitric oxide synthase (iNOS/NOS II) inhibitor. Apoptosis and necrosis inducer. Novel type of inhibitor against RNA guanylyltransferases. Inhibits TNF-alpha-stimulated MAPK/NF-kappaB and ROS generation.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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