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1,3-Dioxoisoindolin-2-yl+isobutyrate
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1,3-Dioxoisoindolin-2-yl+isobutyrate
Supplier:
Adipogen
Description:
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.
Supplier:
MP Biomedicals
Description:
Amphotericin B is a polyene antifungal antibiotic from Streptomyces. It has an affinity for sterols, primarily ergosterols, of fungal cell membranes. It forms channels in the membranes, causing small molecules to leak out which contributes to cell death.
Supplier:
Adipogen
Description:
Tozasertib, or VX-680, is a potent and selective inhibitor of Aurora kinases, particularly Aurora A and B. In vitro, VX-680 blocks cell cycle progression and induces apoptosis in a wide range of human tumor types at low IC(50) values (i.e. 3.38nM for human BE-13 cells, and 14.34nM for NTERA cells). Moreover, VX680, also has very potent Ki values, with inhibition constants (Ki) of 0.6, 18, and 46nM for Aurora A, B, and C, respectively. VX-680 is also effective in vivo, being used in a Caki-1 xenograft model, VX-680 demonstrated a 75.7% (P < 0.001) decrease in Caki-1 xeno-graft tumor volume with no apparent alternation in animal body weight, peripheral blood counts, or other biological parameters.
Supplier:
MP Biomedicals
Description:
(±)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor α (TNF-α); inhibitor of angiogenesis; immunosuppressive; sedative; teratogen.
Supplier:
BeanTown Chemical
Description:
CAS: 326-91-0; EC No: 206-316-7; MDL No: MFCD00005445
Crystalline; Molecular Formula: C8H5F3O2S; MW: 222.18
Melting Point: 40-44°; Boiling Point: 96-98°/8 mmHg; Flash point: 112°C (234°F)
Supplier:
Adipogen
Description:
CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) <lt/> 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCµ), ROCK2, and TBK1 kinase as well.
Supplier:
MilliporeSigma
Description:
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride for synthesis, CAS number 25952-53-8, Chemical formula C8H17N3*HCl 25g
Catalog Number:
(101793-210)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 007672-1G , MDL Number: MFCD03701683
Supplier:
Adipogen
Description:
Bisindoylmaleimide X is a potent and selective protein kinase C (PKC) inhibitor (IC(50) of 15nM for rat brain PKC). It also inhibits Fas-mediated apoptosis and T cell-mediated autoimmune diseases.
Supplier:
Adipogen
Description:
CYC116 is an orally active small molecule multi-kinase inhibitor with anti-neoplastic activity. CYC116 inhibits Aurora kinases A/B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death, and the inhibition of angiogenesis.
Supplier:
Chem Impex International
Description:
A carbodiimide coupling reagent that generates a urea by-product which can be easily removed from the reaction media by extraction with water
Supplier:
AMBEED, INC
Description:
2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene, Purity: 98%, CAS Number: 7128-64-5, Appearance: Form: Crystal - Powder / Colour: Very pale yellow - Pale yellow green - Green, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 25G
Supplier:
Thermo Scientific Chemicals
Description:
2-[3,4-(Methylenedioxy)phenyl]ethylamine, 95%
Catalog Number:
(102987-842)
Supplier:
Adipogen
Description:
Non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, vesicles, cells, tissue and even small whole animals over several days without side effects. Stronger fluorescent intensity under acidic conditions and barely detectable in alkaline solutions (wide range from pH 4 to pH 8). Highly cell/membrane permeable. Trapped within the cells and acidic organelles through hydrophobic interactions with the inner side of the membranes. Barely metabolized and long-term stable, thus slow photobleaching. Angiogenesis inhibitor. Inhibitor of matrix metalloproteinases MMP-1,-2,-8,-9,-12,-13. TYK2, DYRK2,Dyrk1A, YSK4 and RPS6KA1/2 inhibitor.
Supplier:
AAT BIOQUEST INC
Description:
A variety of cyanine dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis.
Supplier:
ALADDIN SCIENTIFIC
Description:
Product Introduction:SU3327 is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM. SU3327 also inhibits protein-protein interactions between JNK and JNK Interacting Protein (JIP) with an IC50 of 239 nM. SU3327 shows less active against p38α and Akt kinase.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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