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4-(Methoxymethyl)-α-methylbenzenemethanol
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4-(Methoxymethyl)-α-methylbenzenemethanol
Catalog Number:
(10751-336)
Supplier:
Prosci
Description:
RASSF10 Antibody: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.
Catalog Number:
(10748-910)
Supplier:
Prosci
Description:
OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains. It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor.
Supplier:
Adipogen
Description:
IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC(50) values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10µM to 200µM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.
Catalog Number:
(10261-428)
Supplier:
Bioss
Description:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
Catalog Number:
(10261-424)
Supplier:
Bioss
Description:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
Supplier:
AMBEED, INC
Description:
2-((2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, Purity: 98%, CAS Number: 1234480-84-2, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 10mg
Catalog Number:
(103008-370)
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 amino acid residues 1-21. It is monomethylated at arginine 17 with a C-terminal GG linker followed by a biotinylated lysine. The methylation of histone H3 at arginine 17 is linked with gene activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTARKSTGGKAP-R(Me1)-KQLA-GGK(Biotin)-NH2 MW:2736.2 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(103011-172)
Supplier:
Anaspec Inc
Description:
Excitation-ratiometric fluorescent indicator for quantifying intracellular Ca2+ concentration
Supplier:
AAT BIOQUEST INC
Description:
Calcium measurement is critical for numerous biological investigations.
Catalog Number:
(103008-078)
Supplier:
Anaspec Inc
Description:
Tat-Glur23Y, scrambled is a control peptide. The synthetic peptide (Tat-Glur23Y), containing tyrosine residues, blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. However, the scrambled version does not have blockade properties. Previous studies show that Tat-Glur23Y, scrambled increase stress levels in mice, while Tat-Glur23Y reduces stress when administered.
Sequence: YGRKKRRQRRRVYKYGGYNE MW: 2634 Da % Peak area by HPLC: 95 Storage condition: -20°C
Catalog Number:
(101837-926)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 034575-500MG , MDL Number: MFCD11506634
Catalog Number:
(103009-504)
Supplier:
Anaspec Inc
Description:
This is a monomethylated lysine at position 9 of the 1-21 amino acid histone H3 peptide. This form of histone methylation is characterized as being enriched around transcription start sites. This peptide has been used as a control peptide in a TR-FRET assay for identifying inhibitors of histone lysine demethylases.
Sequence:ARTKQTAR-K(Me1)-STGGKAPRKQLA MW:2269.1 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(10261-422)
Supplier:
Bioss
Description:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
Supplier:
BeanTown Chemical
Description:
CAS: 13474-03-8; EC No: 224-961-2; MDL No: MFCD08689634; RTECS: AU7481600
Powder; Molecular Formula: C10H13N5NaO7P; MW: 369.20
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 amino acid residues 21 to 44 mono-methylated at Lys-36 with an additional C-terminal glycine followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ATKAARKSAPATGGV-K(Me1)-KPHRYRPG-GK(Biotin) MW:2931.5 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(10484-818)
Supplier:
Bioss
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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