Nonadecanoic acid methyl ester
Supplier:
Matrix Scientific
Description:
MF=C8H8F2O MW=158.15 MDL=MFCD01631321 1G
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00008404
Beilstein Registry No.: 1878026
Catalog Number:
(102535-888)
Supplier:
Matrix Scientific
Description:
MF=C7H6FNO3 MW=171.13 CAS=61324-93-4 MDL=MFCD11848442 5G
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine 96%
Supplier:
TCI America
Description:
Alibendol, Purity: >98.0%(GC), CAS Number: 26750-81-2, Molecular Formula: C13H17NO4, Molecular Weight: 251.28, Synonyms: 5-Allyl-N-(2-hydroxyethyl)-3-methoxysalicylamide, Size: 5G
Supplier:
AMBEED, INC
Description:
ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na, oxidized form) 99%
Supplier:
BeanTown Chemical
Description:
CAS: 171876-65-6; MDL No:
MFCD03428534
Solid; Molecular Formula: C10H10O4·C4H10N2; MW: 280.32
Supplier:
Adipogen
Description:
GSK2126458 is an orally available selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzymesand MTOR1/2 complexes. GSK2126458 can inhibit PI3K-alpha (p85alpha/p110alpha) with IC(50) of 0.04nM. GSK2126458 has Ki values in the picomolar range for each of the class I PI3K isoforms and MTOR1/2 complexes. GSK2126458 has potent in vitro and in vivo growth-inhibitory effects on cancer cells. In comparison with other clinical PI3K inhibitors, GSK2126458 is around 100-fold more potent than BEZ235 (6nM). GSK2126458 also a low picomolar inhibitor of the common activating mutants of p110R ( E542K, E545K, and H1047R ) with Ki of 0.008nM, 0.008nM and 0.009nM in human cancer. In mechanistic cellular assays, GSK2126458 caused a significant reduction in the levels of pAKT-S473 with remarkable potency. Consistent with its activity against both PI3K R and mTOR, GSK2126458 also inhibits phosphorylation of AKT-T308 and p70S6K at low nanomolar concentrations. GSK2126458 induces a G1 cell cycle arrest and inhibits cell proliferation in a large panel of cell lines, including T47D and BT474 breast cancer lines.
Catalog Number:
(101831-268)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 031151-500MG , MDL Number: MFCD00870510
Catalog Number:
(102539-888)
Supplier:
Matrix Scientific
Description:
MF=C8H8O3 MW=152.15 CAS=148-53-8 MDL=MFCD00003322 100G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044094-5G , MDL Number: MFCD00172032
Catalog Number:
(10067-270)
Supplier:
Thermo Scientific Chemicals
Description:
A broad spectrum macrolide antibiotic structurally related to erythromycin. Azithromycin dihydrate has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis
Supplier:
Adipogen
Description:
Benzoquinone ansamycin antibiotic
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