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1H-Pyrrolo[3,2-c]pyridine-7-carboxylic+acid
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1H-Pyrrolo[3,2-c]pyridine-7-carboxylic+acid
Supplier:
AMBEED, INC
Description:
Ethyl-2-methyl-1H-pyrrole-3-carboxylate 98%
Catalog Number:
(77014-616)
Supplier:
AMBEED, INC
Description:
Ethyl-1H-indazole-7-carboxylate 97%
Supplier:
Matrix Scientific
Description:
Ethyl 3-{[4-(4-Chlorophenyl)Piperazin-1-Yl]Sulfonyl}-1H-Pyrazole-4-Carboxylate, MF=C16H19CLN4O4S, MW=398.87, CAS=1261016-92-5, 500MG
Supplier:
AMBEED, INC
Description:
Methyl-4-bromo-1-methyl-1H-pyrazole-3-carboxylate 97%
Supplier:
TCI America
Description:
CAS Number: 72558-82-8
MDL Number: MFCD00072034 Molecular Formula: C22H22N6O7S2 Molecular Weight: 546.57 Form: Crystal Color: White
Supplier:
AMBEED, INC
Description:
Methyl 1H-pyrazole-3-carboxylate, Purity: 98%, CAS Number: 15366-34-4, Appearance: Form: Crystal - Powder / Colour: White - Pale-yellow, Storage: Inert atmosphere, Room Temperature, Size: 10G
Supplier:
AMBEED, INC
Description:
Methyl-5-phenyl-1H-pyrazole-3-carboxylate 96%
Catalog Number:
(101924-624)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062829-500MG , MDL Number: MFCD04969151
Supplier:
AMBEED, INC
Description:
Ethyl 6-fluoro-1H-indole-2-carboxylate, Purity: 97%, CAS Number: 348-37-8, Appearance: Form: solid, Storage: Sealed in dry, Room Temperature, Size: 100mg
Supplier:
AMBEED, INC
Description:
Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoate hydrochloride, Purity: 98%, CAS Number: 1797983-09-5, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 25mg
Supplier:
AMBEED, INC
Description:
Methyl 3-methyl-1H-pyrrole-2-carboxylate 97%
Supplier:
AMBEED, INC
Description:
Ethyl-5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate 95%
Supplier:
Adipogen
Description:
Antagonizing the Chk1-mediated cell cycle checkpoints has emerged as an attractive target for anticancer therapy. If Chk1 activity is blocked, DNA-damaged or spindle-disrupted cells would exit cell cycle arrest before full repair and subsequently undergo mitotic catastrophe or cell death. Chk1 inhibitors consequently increase the therapeutic index of DNA-damaging or antimitotic agents as well. PF-0477736 is a selective, potent ATP-competitive Chk1 inhibitor, derived from PF-0394691, inhibits Chk1 (Ki, 0.49nM) and Chk2 (Ki, 47nM) in vitro. In tests, PF-0477736 was identified as a potent, selective ATP-competitive small-molecule inhibitor that inhibits Chk1 with a Ki of 0.49nM. PF-0477736 abrogates cell cycle arrest induced by DNA damage and enhances cytotoxicity of clinically important chemotherapeutic agents, including gemcitabine and carboplatin. In xenografts, PF-0477736 enhanced the antitumor activity of gemcitabine in a dose-dependent manner. PF-0477736 combinations were well tolerated with no exacerbation of side effects commonly associated with cytotoxic agents.
Catalog Number:
(102897-754)
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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