2,7-Diaminofluorene+dihydrochloride
Supplier:
AMBEED, INC
Description:
(4-(Pyridin-2-yl)phenyl)boronic acid, Purity: 98%, CAS number: 170230-27-0, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 5G
Supplier:
AMBEED, INC
Description:
2-(Phenylthio)isoindoline-1,3-dione, Purity: 95%, CAS Number: 14204-27-4, Appearance: White to Light yellow powder to crystal, Storage: Sealed in dry, Room Temperature, Size: 250mg
Catalog Number:
(PI88432)
Supplier:
Invitrogen
Description:
Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.
Supplier:
AMBEED, INC
Description:
1-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, Purity: 97%, CAS Number: 40733-27-5, Appearance: White to off-white solid, Storage: Sealed in dry, 2-8 deg C, Size: 1mg
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Trypan blue
Supplier:
AOB CHEM USA
Description:
tert-Butyl 2,3-difluorobenzoate ≥97%
Catalog Number:
(75928-892)
Supplier:
Rockland Immunochemical
Description:
Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.
Catalog Number:
(AAAB24680-06)
Supplier:
AOB CHEM USA
Description:
2-(Benzyloxy)-4-(tert-butyl)benzaldehyde ≥95%
Supplier:
AMBEED, INC
Description:
trans-4-(Hydroxymethyl)cyclohexanol 98%
Supplier:
Spectrum Chemicals
Description:
BSE/TSE statement (available upon request)
Allergen statement (available upon request)
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Supplier:
AOB CHEM USA
Description:
(3,4-difluoro-2-methoxyphenyl)(4-methylpiperazin-1-yl)methanone ≥97%
Catalog Number:
(77145-334)
Supplier:
AMBEED, INC
Description:
5-Bromo-4-fluoroindoline, Purity: 95%, CAS Number: 1782463-27-7, Appearance: Solid or semi-solid or lump or liquid, Storage: Keep in dark place, Inert atmosphere, 2-8 deg C, Size: 100mg
Supplier:
AMBEED, INC
Description:
2-Fluoro-3-iodobenzonitrile, Purity: 95%, CAS number: 211943-27-0, Appearance: Pale-yellow to Yellow-brown Solid, Storage: Keep in dark place, Sealed in dry, 2-8C, Size: 250MG
Catalog Number:
(77237-832)
Supplier:
AMBEED, INC
Description:
4-Bromo-8-methyl-1,5-naphthyridine, Purity: 97%, CAS Number: 1432323-27-7, Appearance: Light-brown to brown powder or crystals, Storage: Inert atmosphere, 2-8 C, Size: 5g
Catalog Number:
(10750-384)
Supplier:
Prosci
Description:
EBI3 Antibody: EBI3 is a subunit in two distinct heterodimeric cytokines: interleukin-27 (IL-27) and IL-35. Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 (also known as TCCR) and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet. IL-35 is composed of EBI3 and the p35 subunit of IL-12 and has been reported to have therapeutic effects against collagen-induced arthritis by expanding the population of regulatory T cells and suppressing Th17 cells. At least two isoform of EBI3 are known to exist.
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